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    Did you mean Adrenal Cortical Carcinoma?
    GlossaryAdrenocortical Carcinoma

    rare cancer in adrenal gland's outer layer causing hormone imbalance

    Adrenocortical Carcinoma (ACC), also known as Adrenal Cortex Cancer, is a rare and aggressive cancer that originates in the outer layer (cortex) of the adrenal glands, which are small glands located on top of each kidney. These glands produce hormones like cortisol, aldosterone, and androgens, which regulate various bodily functions. ACC can lead to an overproduction of these hormones, causing symptoms such as high blood pressure, weight gain, and hormonal imbalances. Early detection and treatment are crucial for improving outcomes.

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      a synthetic cortisol used for anti-inflammatory effects

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      community Now i want to see if this DHT survives

      in Treatment  34 upvotes 2 days ago
      The conversation discusses using minoxidil, finasteride, spironolactone, and RU58841 for hair loss treatment. Users share experiences with these treatments, noting side effects and varying effectiveness.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  7 upvotes 4 days ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community My personal thoughts on DHT. belive it or not

      in Research/Science 7 months ago
      The conversation discusses a personal theory on the role of DHT in stress and reproduction, suggesting it converts testosterone for reproductive traits. The discussion includes skepticism and mentions individual differences in physiology and neurochemistry.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 1 year ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.