441 citations,
May 2008 in “British Journal of Pharmacology” Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
56 citations,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
21 citations,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
Continuous research and innovative strategies are essential for sustainable development.
June 2016 in “CRC Press eBooks” Sleep problems and skin issues affect each other; poor sleep can worsen skin conditions, and some skin treatments can improve or harm sleep quality.
658 citations,
June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
82 citations,
February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.
57 citations,
June 2003 in “American Journal of Physiology-cell Physiology” Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
13 citations,
June 2020 in “BMC genomics” A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
1 citations,
November 2021 in “American Journal of Clinical Pathology” The conclusion is that certain physical signs in the body can indicate past acute and chronic stress, which may help in child abuse investigations.
8 citations,
May 2017 in “Current traditional medicine” Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.
3 citations,
March 2017 in “Regulatory toxicology and pharmacology” Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
September 2005 in “Clinics in Plastic Surgery” The document provides a comprehensive index of medical and surgical topics, including hair removal, hair restoration, and various treatments for injuries and conditions.
69 citations,
November 2010 in “Middle East Fertility Society Journal” PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
54 citations,
May 1998 in “Urology” Men with enlarged prostates often have more severe baldness.
112 citations,
January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
2 citations,
October 1998 in “Family Practice” New oral treatment, finasteride, effectively and safely treats common hair loss.
43 citations,
January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
May 2020 in “Fertility and Sterility” Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.
3 citations,
September 2021 in “International Journal of Molecular Sciences” Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
October 2021 in “International Journal of Andrology” Finasteride, a hair loss drug, has unaddressed sexual side effects due to the manufacturer's inadequate safety measures and lack of additional studies.
29 citations,
June 2020 in “International Journal of Molecular Sciences” Notch signaling disruptions can cause various skin diseases.
2 citations,
January 2022 in “The Application of Clinical Genetics” A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.
43 citations,
July 2003 in “Andrology” Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.
3 citations,
March 2022 in “Transgender Health” More research is needed to improve lower body gender affirmation techniques.
3 citations,
June 2018 in “The New England Journal of Medicine” A woman with Cushing's syndrome improved after surgery to remove a tumor causing the condition.
32 citations,
January 2006 in “Liver transplantation” Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.
May 2023 in “IntechOpen eBooks” More research is needed to understand how testosterone is maintained in adult males.
The document concludes that hair loss in women is complex, often linked to aging, health conditions, and nutritional deficiencies, and emotional impacts should not be underestimated.
76 citations,
December 2009 in “Clinics in Dermatology” Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.