7 citations
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January 2013 in “Hormone Research in Paediatrics” This case report describes an adult female with congenital adrenal hyperplasia who developed secondary amenorrhea and hair loss due to androgen overproduction from ovarian adrenal rests, detectable only after pelvic venous sampling, and normalizing after unilateral oophorectomy.
November 2025 in “Frontiers in Endocrinology” This study indicated that prediabetes may make ovaries more susceptible to PCOS-like changes, with mild hyperglycemia potentially having harmful effects on ovarian health.
8 citations
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October 2022 in “International Journal of Molecular Sciences” This review explores the potential of self-amplifying RNA technology for protein replacement therapy in various health disorders but reports no new experimental results, indicating challenges remain for clinical approval.
12 citations
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May 2005 in “Journal of the American Geriatrics Society” This case report describes successful treatment of valproate-induced hyperammonemia in a 79-year-old man using lactulose, marking the first such documented use for this condition.
19 citations
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January 2007 in “Biological & pharmaceutical bulletin” This study found that glycine treatment inhibited melanogenesis in B16F0 melanoma cells and reduced melanin content in C57BL/6J mice by down-regulating tyrosinase protein levels.
May 2019 in “Clinica chimica acta” This study reported that mice with more diverse gut microbiota showed higher hair levels of certain hormones and 1-AG compared to those with less diverse microbiota, though plasma differences were more complex and varied by stress and sex.
5 citations
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October 2013 in “Experimental Dermatology” This study observed that putrescine and HR form a negative feedback mechanism affecting hair cycling, indicating a significant connection between HR, polyamines, and hair growth regulation.
9 citations
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August 1952 in “The Journal of Clinical Endocrinology & Metabolism” This study describes a method to estimate endogenous hormone production by neutralizing an endogenous hormone with an oppositely acting hormone.
October 2022 in “The Egyptian Journal of Hospital Medicine” In this study, serum omentin-1 levels were higher in females with idiopathic hirsutism compared to those with hirsutism and polycystic ovary syndrome, suggesting it may help distinguish between these conditions.
2 citations
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September 2008 in “Fertility and Sterility” In this study, biochemical and clinical hyperandrogenism in PCOS were found to be distinct entities with no strong androgen correlation to clinical symptoms like acne or hirsutism.
29 citations
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January 2006 in “Clinical chemistry and laboratory medicine” This study found that male liver cirrhosis patients have higher estradiol levels and lower dehydroepiandrosterone sulfate, leading to hormonal imbalances favoring estradiol, but without changing sex hormone-binding globulin's binding properties.
23 citations
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June 2015 in “Clinica Chimica Acta” In this study, researchers identified two potential urinary biomarkers, testosterone–glucuronide and 11α-hydroxyprogesterone, along with four candidate biomarkers, to help understand and diagnose polycystic ovary syndrome.
28 citations
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November 2013 in “The FASEB journal” In this study, a low-methionine diet significantly improved the health and physical traits of cystathionine β-synthase-deficient mice, contrasting with negative effects on mice with partial deficiency.
28 citations
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November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study indicates that the normal human prostate is not a major contributor to circulating blood DHT concentrations in androgen-deficient patients receiving testosterone replacement therapy.
5 citations
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August 2015 in “Sultan Qaboos University medical journal” This case report highlights an atypical presentation of vitamin B12 deficiency in a 28-year-old man with reversible symptoms including localized hand hyperpigmentation and megaloblastic anemia, resolved after B12 supplementation.
9 citations
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December 1987 in “Archives of Dermatology” This study highlights two newly discovered metabolic disorders of biotin, showing distinct skin and hair symptoms and severe complications like acidosis and ketosis.
2 citations
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June 2020 in “AIDS” This case study describes a severe instance of iatrogenic Cushing's syndrome induced by gamma-hydroxybutyric acid, exacerbated by combined use of betamethasone and anabolic steroids, in an HIV-positive patient on cobicistat-containing therapy.
1 citations
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February 2023 in “Animals” In this study, the inclusion of a feedstuff high in energy along with soybean meal enhanced body condition, body mass index, and reproductive performance in sheep fed low-protein forage.
2 citations
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October 2021 in “Research Square (Research Square)” This study found that in patients undergoing allogeneic hematopoietic stem-cell transplantation, older age significantly increases the risk of hemorrhagic cystitis, especially in males, who are also affected by prostatic hyperplasia.
This study found that a protein-sparing modified fast may safely and effectively help maintain weight loss over a short period when supervised by a physician.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case study describes a rare instance of virilization during pregnancy in a woman with PCOS, with symptoms resolving post-delivery as testosterone levels normalized.
December 2023 in “American journal of medical genetics. Part A” In this study, researchers identified compound heterozygous variants in the MBTPS1 gene associated with ectodermal dysplasia features in a 14-year-old female, broadening the known disorder spectrum linked to these genetic mutations.
11 citations
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January 2023 in “World Journal of Clinical Cases” This study suggests that idiopathic hirsutism may involve higher local androgen synthesis despite normal serum androgen levels, challenging its categorization as idiopathic.
January 1986 in “Journal of Steroid Biochemistry” Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
2 citations
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September 1993 in “PubMed” In this case report, a young man with primary hypothyroidism caused by autoimmune atrophic thyroiditis showed full recovery and normalization of metabolism after levothyroxine treatment.
6 citations
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December 2022 in “Anais Brasileiros de Dermatologia”
1 citations
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July 2022 in “Clinical and Experimental Dermatology” This study suggests that arginine and cysteine deficiency is not present in women with chronic telogen effluvium, indicating that amino acid supplementation may be unnecessary in nutrient-replete populations.
49 citations
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January 1972 in “Biochimica et Biophysica Acta (BBA) - Protein Structure”
January 2021 in “Turkiye Klinikleri Journal of Dermatology” This study found that female patients with telogen effluvium had significantly lower serum prolactin levels compared to healthy controls, which contrasts with previous findings linking higher prolactin to hair loss.
3 citations
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June 2024 in “Journal of Neuroendocrinology” This study observed that many women with PCOS had unfavorable lipoprotein profiles, mostly moderate changes in triglycerides, HDL, and LDL cholesterol, with small LDL particles not being rare and potentially aiding risk assessment.