Hairy Pregnancy: A Case of Gestational Hyperandrogenism

    Nur Hidayah Mohd Makhatar, Subashini Rajoo
    Studysummary This case study describes a rare instance of virilization during pregnancy in a woman with PCOS, with symptoms resolving post-delivery as testosterone levels normalized.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The article discusses a rare case of gestational hyperandrogenism in a 27-year-old woman with a history of polycystic ovarian syndrome (PCOS), who experienced increased hair growth during pregnancy. Despite elevated testosterone levels, which are typically managed by increased sex hormone-binding globulin (SHBG) and placental aromatase, the patient's PCOS diminished these protective effects, leading to clinical hyperandrogenism. Post-delivery, her symptoms resolved, and testosterone levels normalized, although PCOS symptoms may recur. This case highlights the complex interplay between pregnancy, testosterone, and PCOS.
    Discuss this study in the Community →