TLDR A woman's increased hair growth during pregnancy due to PCOS resolved after delivery.
The article discusses a rare case of gestational hyperandrogenism in a 27-year-old woman with a history of polycystic ovarian syndrome (PCOS), who experienced increased hair growth during pregnancy. Despite elevated testosterone levels, which are typically managed by increased sex hormone-binding globulin (SHBG) and placental aromatase, the patient's PCOS diminished these protective effects, leading to clinical hyperandrogenism. Post-delivery, her symptoms resolved, and testosterone levels normalized, although PCOS symptoms may recur. This case highlights the complex interplay between pregnancy, testosterone, and PCOS.
19 citations,
July 2013 in “The obstetrician & gynaecologist” The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
467 citations,
October 2014 in “European Journal of Endocrinology” The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.
58 citations,
November 2020 in “International Journal of Molecular Sciences” SHBG may be a useful early indicator and treatment target for PCOS.
September 2023 in “Research Square (Research Square)” Evening primrose oil significantly improves hormone levels and reduces BMI and cholesterol in women with PCOS.
November 2018 in “International Journal of Current Pharmaceutical Research” PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.
124 citations,
June 2002 in “Best Practice & Research Clinical Endocrinology & Metabolism” Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.