This correspondence suggests that while patients with Raynaud phenomenon may develop connective tissue disorders, physicians should consider this possibility without assuming for certain that progression will occur.
1 citations
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October 2024 in “Indian Dermatology Online Journal” This case report describes a 36-year-old man who developed generalized eruptive histiocytosis on the scalp after undergoing nine platelet-rich plasma treatments for hair loss, likely triggered by injection-related trauma and inflammation.
11 citations
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March 1991 in “PubMed” This study found that in female patients with androgenic hair loss and hirsutism, complex hormonal disturbances include elevated cortisol and thyroid hormone imbalances, rather than elevated androgen levels alone.
74 citations
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January 2014 in “Journal of Investigative Dermatology” High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
112 citations
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January 2013 in “Experimental dermatology” This article offers a viewpoint on hidradenitis suppurativa pathogenesis, suggesting that impaired Notch signalling from γ-secretase mutations may drive inflammation and link the condition to other Th17-driven diseases.
January 2025 in “Open Life Sciences” This study observed that transgenic mice with overexpression of HE4 developed keratitis and severe corneal opacity, suggesting that HE4 may significantly influence keratopathy and inflammatory responses in the eye.
37 citations
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December 2007 in “International journal of clinical practice” This review discusses the definition, pathogenesis, diagnosis, and management of hirsutism and reports no new clinical results.
October 2022 in “European heart journal” In this study, stress levels measured through hair cortisol concentration gradually increased in the days before an acute myocardial infarction, peaking 15 days before the episode in male patients.
June 2024 in “International journal of biological macromolecules” This study reports that beta-glucan hybrid hydrogels, reinforced with laponite nanoclay, showed promising results in rat models for managing hemorrhage and diabetic wound healing by enhancing hemostasis, reducing inflammation, and promoting faster wound closure and tissue regeneration.
35 citations
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March 2012 in “Experimental and Clinical Endocrinology & Diabetes” This article discusses various causes of hyperandrogenism in women and highlights diagnostic considerations for conditions such as PCOS, NCCAH, Cushing's disease, and androgen-secreting tumors, without reporting new clinical results.
This section presents 70 multiple choice questions designed for haematology specialist trainees, covering complex clinical cases and their likely diagnoses, adverse events, and management advice.
This study found significant variability in the production and use of platelet-rich plasma and related products in Brazil, highlighting the need for regulatory measures to ensure safety.
April 2019 in “Journal of Investigative Dermatology” The study suggests that variability in platelet-derived growth factors in PRP is influenced by both patient-to-patient differences and the devices used for PRP preparation, contributing to inconsistent clinical outcomes in hair loss treatments.
4 citations
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May 2023 in “JAAD case reports” This study highlights the significant risk of vascular embolism associated with hyaluronic acid filler injections, emphasizing concerns about potential irreversible damage when fillers are injected in "unexplored" facial areas due to complex and variable facial anatomy.
4 citations
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May 2014 in “Journal of Cutaneous Medicine and Surgery” Platelet-rich plasma may help with wound healing, hair growth, and skin rejuvenation, but more research is needed to prove its effectiveness.
February 2010 in “Journal of The American Academy of Dermatology” Women with androgenetic alopecia may have higher blood pressure levels.
13 citations
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May 2012 in “Cutaneous and ocular toxicology” In this study, researchers found no significant differences in vitamin B12, folate, and homocysteine metabolism between patients with alopecia areata and controls, suggesting no association with vitamin B12 deficiency.
4 citations
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July 2017 in “Journal of Medical Case Reports” This case report highlights a rare presentation of acute lupus hemophagocytic syndrome with initially negative antinuclear antibodies, underscoring the higher sensitivity of the 2012 Systemic Lupus International Collaborating Clinics criteria for diagnosis.
77 citations
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August 1986 in “Archives of Dermatology” This report describes a case in which intramuscular cyanocobalamin treatment reversed skin and nail pigmentation changes and premature gray hair caused by vitamin B12 deficiency due to pernicious anemia.
1 citations
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September 2002 in “European Journal of Endocrinology” This case study reports the clinical features of triple H syndrome in a 25-year-old man, including ACTH deficiency, alopecia universalis, and anterograde amnesia, which were improved with hydrocortisone treatment.
July 2007 in “Hair transplant forum international” This article discusses advancements in hair transplant procedures that allow for more follicular units to be transplanted per session but notes the lengthy procedure time required.
1 citations
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February 2005 in “The Lancet” Hair loss may be linked to cardiovascular health problems.
November 2015 in “Clin-Alert” Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.
January 2020 in “Medical journal of Dr. D.Y. Patil Vidyapeeth” This study found that polycystic ovarian syndrome (PCOS) is the most common cause of cutaneous manifestations of hyperandrogenism in women of reproductive age, with hirsutism severity correlated to serum testosterone levels.
April 2018 in “Journal of Investigative Dermatology” This study found that patients taking hydroxychloroquine had a significantly higher likelihood of indeterminate QuantiFERON-TB Gold test results compared to those not on the medication, independent of other immunosuppressive drug use.
4 citations
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May 2008 in “Clinics in Dermatology” Skin problems can indicate different diseases inside the body.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This pilot study suggests that a new preparation of platelet-rich plasma gel may improve symptoms and tissue regeneration in patients with en coup de sabre scleroderma, though further trials are needed to clarify its role.
April 2024 in “International Journal of Advanced Research” In this case-control study, researchers observed that vitamin B12 deficiency was significantly associated with diffuse hair loss and muco-cutaneous pigmentation in patients, suggesting these may serve as clinical markers for dermatologists to consider when diagnosing vitamin B12 deficiency.
This review discusses the generally well-tolerated use of PRP and microneedling, detailing mild adverse events like transient pain and rare severe complications such as irreversible blindness, emphasizing the need for proper technique and precautions to prevent these issues.
21 citations
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March 2023 in “Journal of Crohn s and Colitis” This study suggests that microvascular damage and platelet deregulation may persist in ulcerative colitis patients even during remission, remaining as disease-associated molecular signatures.