1 citations
,
January 1979 in “International Journal of Dermatology” This article reviews the use of anti-androgens, particularly cyproterone acetate, for managing hirsutism, but does not provide new clinical results.
8 citations
,
January 1996 in “Gynecological Endocrinology” This review evaluates therapies for hyperandrogenism, highlighting cyproterone acetate as the preferred treatment due to its potency and tolerability in managing symptoms in women.
August 2013 in “Fertility and Sterility” This study found that androgenic alopecia is common in polycystic ovary syndrome, correlates with other hyperandrogenism signs, but not with increased biochemical or metabolic risk compared to PCOS alone.
1 citations
,
May 2011 in “Journal of Obstetrics and Gynaecology” Hair loss in postmenopausal women due to ovarian hyperthecosis is rare, but removing the ovaries can significantly improve the condition.
February 2025 in “Cureus” This case report describes a 37-year-old female with non-classical congenital adrenal hyperplasia who presented with severe acne, progressive hair loss, and primary infertility, managed with prednisolone.
December 2000 in “Journal of the Royal Society of Medicine” Antiandrogen therapy may help treat hidradenitis suppurativa.
21 citations
,
May 2001 in “PubMed” This paper reviews the significance of androgen hormones in hair and skin conditions like alopecia, hirsutism, and acne, and reports no new clinical findings.
55 citations
,
May 2019 in “Journal of Endocrinology” This review summarizes research on androgens' roles in female reproductive function, noting their impact on IVF outcomes and the development of PCOS, and highlights the need for mechanism-based therapies.
50 citations
,
April 2010 in “Biology direct” This study's model suggests that low androgen levels can increase selection for prostate cancer phenotypes resistant to hormonal therapy, potentially leading to more aggressive forms of cancer.
5 citations
,
October 2014 in “Gynecological Endocrinology” This case study describes a 15-year-old girl with a Sertoli–Leydig cell tumor who showed high androgen levels and steroidogenic responses similar to patients with polycystic ovary syndrome before surgery.
6 citations
,
March 1982 in “Clinical and Experimental Dermatology” This article discusses primary cutaneous virilism, focusing on alopecia in women with androgen-dependent skin conditions, and reports no new findings.
31 citations
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April 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study found that active androgens activate lipogenic differentiation in human sebocytes expressing a functional androgen receptor, influencing gene expression and lipid synthesis, while also increasing apoptotic cell population over time.
13 citations
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January 2012 in “International Journal of Trichology” In this study, idiopathic hirsutism was identified as the most common cause of hirsutism among the participants, with a significant difference in hormone levels between cases of polycystic ovarian syndrome and idiopathic hirsutism.
6 citations
,
January 2001 in “Cambridge University Press eBooks” This review discusses how androgen excess in polycystic ovary syndrome can lead to hirsutism, seborrhea, and worsen conditions like androgenetic alopecia and acne, but includes no new research findings.
40 citations
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November 2013 in “European journal of endocrinology” This paper reviews the treatment options for hirsutism and emphasizes the importance of diagnosing its underlying cause and considering patient perception and specific phenotypes, reporting no new clinical results.
January 2019 in “Paëmi Sino” This study found that acne and androgenic alopecia were prevalent in women with "true" keloids, suggesting hormonal imbalances may contribute to keloid formation.
January 2025 in “Case Reports in Medicine” In this case study, a diagnosis of HAIR-AN syndrome, a rare form of polycystic ovarian syndrome, was made in a 17-year-old female with hyperandrogenism, insulin resistance, and acanthosis nigricans, but genetic screening revealed no significant mutations linked to her symptoms.
48 citations
,
January 2000 in “Hormone Research in Paediatrics” This article reviews the regulation of androgens in human skin and adrenals, highlighting their role in skin disorders, but reports no new research findings.
7 citations
,
August 2012 in “The Journal of Urology” This study found that despite androgen excess and genitourinary masculinization, adult women with congenital adrenal hyperplasia did not exhibit notable prostatic growth.
September 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”
December 2023 in “International Journal of Research in Dermatology” This study evaluated hormonal differences in males with early androgenetic alopecia, finding increased serum testosterone, prolactin, LH, LH/FSH, and FAI levels, with decreased FSH and SHBG levels, compared to controls without hair loss.
June 2026 in “Romanian Journal of Medical Practice” This case report describes a 72-year-old woman with a steroid cell tumor of the ovary, highlighting the critical role of imaging, biochemical evaluation, and pathology in diagnosing and managing hormonally active ovarian tumors that cause virilization in postmenopausal women.
January 2021 in “touchREVIEWS in Endocrinology” Surgery successfully treated a hidden ovarian tumor causing hair loss and excess hair growth in a postmenopausal woman.
21 citations
,
October 2009 in “Dermatology” This study found that male pattern hair loss may be associated with differences in serum levels of androstenedione, cortisol, 17 beta-estradiol, and luteinizing hormone, compared to controls.
25 citations
,
September 2015 in “Clinical Endocrinology” This study found that diagnosing nonclassic congenital adrenal hyperplasia in women based solely on serum 17OHP measurements can lead to false positives, suggesting the need for urinary steroid profiles and genetic testing for confirmation.
October 2024 in “InnovAiT Education and inspiration for general practice” In this article, the authors review the causes, diagnosis, and treatment approaches for hirsutism in women, emphasizing diagnosis, hormonal therapies, lifestyle modifications, and cosmetic options for managing this condition in primary care settings.
10 citations
,
May 1995 in “Journal of General Internal Medicine” Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
53 citations
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December 2015 in “JAMA Dermatology” This study found that hirsutism and acanthosis nigricans are the most reliable skin markers for diagnosing polycystic ovary syndrome in women and suggest a need for further evaluation of possible metabolic issues.
April 2024 in “Women s Health Reports” This study explored the clinical and biochemical hyperandrogenic status in adolescents with irregular menses to identify significant indicators of potential metabolic problems linked to PCOS.
January 2024 in “Brazilian Journal of Hair Health” This article discusses the role of androgens in androgenetic alopecia and suggests exploring additional causes and pathways involved, but reports no new clinical findings.