39 citations
,
February 1990 in “The journal of cell biology/The Journal of cell biology” This study identified trichohyalin as an early differentiation marker in hair follicles, with potential structural roles related to alpha-helical formations, based on the partial characterization of its cDNA in sheep.
9 citations
,
June 1947 in “Analytical Chemistry” Cold waving solutions quickly reduce cystine to cysteine in hair.
226 citations
,
January 2002 in “Biological and Pharmaceutical Bulletin” This study developed a rapid method to extract proteins from human hair, revealing phosphorylation on serine and threonine residues in alpha-keratins and matrix proteins.
March 2026 in “Food Science and Biotechnology” In this study, oral administration of blue honeysuckle fruit extract was found to promote hair growth in mice by enhancing dermal papilla cell proliferation and activating β-catenin signaling, suggesting its potential use as a food or cosmetic product for hair regeneration.
1 citations
,
June 2014 in “[Thesis]. Manchester, UK: The University of Manchester; 2014.” This study found that chemically modifying human hair through esterification or disulfide reduction and alkylation affects the hair's viscoelastic properties, including stability, integrity, and response to moisture.
7 citations
,
June 1989 in “Steroids” In this study, the synthesis of C-4 and C-6 bridged haptens of 11 alpha-hydroxyprogesterone revealed an unexpected formation of a C-4 substituted product using a 6-bromo derivative, contrary to prior reports.
16 citations
,
January 2017 in “Physical chemistry chemical physics/PCCP. Physical chemistry chemical physics” This study presents computational modeling and experimental analysis of the HGT protein KAP8.1, identifying key structural features that may influence hair's response to environmental conditions.
20 citations
,
January 2017 in “Genetica” This study suggests that the methylation degree of HOXC8 exon 1 in the hair follicle may influence cashmere fiber growth in Liaoning cashmere goats.
This study purified trichohyalin protein from pig tongue epithelium, characterizing its unique properties and structure, which may facilitate future functional research.
20 citations
,
December 2012 in “Journal of molecular structure” This study found that at pH 9.0, CYS penetrated less and caused less damage to virgin human hair than TG because it barely reached the cortex region.
July 2026 in “Preprints.org” In this study, incorporating a novel amino acid compound into a hair-straightening formulation improved humidity-resistant straightening and enhanced the surface and mechanical properties of hair fibers, including increased bending stiffness, reduced friction, and better shape retention under high temperature and humidity conditions.
January 2005 in “Life sciences” This review discusses the pathophysiologic role of lysophosphatidic acid in the skin and reports no clinical results, suggesting pharmacological inhibition as a potential treatment for various skin disorders.
106 citations
,
December 2015 in “Biomacromolecules” This study describes a method to create keratin hydrogels with adjustable erosion rates by mixing different ratios of keratose and kerateine, enabling controlled release of therapeutic agents like insulin-like growth factor 1.
10 citations
,
August 2013 in “Experimental Dermatology” This study found that Hairless (HR) and putrescine form a negative regulatory network that impacts epidermal homeostasis and hair follicle cycling, linked to the MYC superfamily's regulation of ODC expression.
1 citations
,
August 2014 in “OhioLink ETD Center (Ohio Library and Information Network)” This research provides insights into how keratin hydrogels, modified to control disulfide crosslinking, may function as a treatment platform for bone injuries.
7 citations
,
December 1956 in “Science” 1 citations
,
December 1956 in “Science”
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses how activating the hexosamine pathway may enhance skin homeostasis by increasing hyaluronic acid secretion and supporting hair follicle stem cell self-renewal, but reports no new results.
6 citations
,
January 2005 in “PubMed” This study found that treating hair with a 1% cotton honeydew extract improves smoothness and reduces chipping compared to untreated hair, confirmed by clinical and SEM evaluations.
January 2002 in “中国人民解放军军医大学学报(英文版)” This study found that human hair keratin scaffold material implanted in damaged rabbit muscle tissue degrades via the ubiquitin system and is further processed by macrophagocytes and lysosomes.
1 citations
,
May 2013 in “PubMed” This study found that glycylglycine treatment improved hair softness by enhancing hair alignment and altering internal fiber properties among Japanese women with typically coarse hair.
This study found that a blend of low- and high-molecular weight hyaluronic acid significantly improved penetration into the hair cortex compared to individual HA types, reducing frizz and increasing hair elasticity and water content, as measured by Confocal Raman Spectroscopy.
79 citations
,
March 2005 in “Journal of Medical Genetics” This study identified a novel heterozygous missense mutation in the hHb3 gene associated with monilethrix, highlighting its role in this hair disorder.
May 2026 in “Fibers and Polymers” September 2016 in “Toxicology letters” The researchers reported that hydrogels made from methacrylated glycol chitosan and hyaluronic acid with chondroitin sulfate may be suitable for load bearing soft tissue repair, showing enhanced chondrocyte viability and metabolic activity.
4 citations
,
August 2024 in “Journal of Cosmetic Dermatology” This study reports that injecting a non-cross-linked hyaluronic acid compound into keratosis pilaris-affected skin led to significant improvements in roughness, redness, and overall skin condition, while maintaining a favorable safety profile, making it a promising alternative treatment option.
20 citations
,
December 1999 in “Journal of Investigative Dermatology” Mutations in the hHb6 gene cause the hair disorder monilethrix.
24 citations
,
July 2022 in “Journal of Applied Pharmaceutical Science” This review discusses the aesthetic and dermatological uses of exogenous hyaluronic acid for skin rejuvenation and highlights the need for thorough investigation to confirm its claimed benefits, but it reports no new clinical findings.
34 citations
,
November 1998 in “Journal of Investigative Dermatology” A common mutation in the hHb6 gene is linked to monilethrix, but other factors may also play a role.
2 citations
,
January 1975 in “Archives of Dermatological Research” Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.