Hyaluronic Acid: Elucidating Its Penetration Into and Effect on Hair Fibers Using Confocal Raman Spectroscopy and Biometric Techniques

January 2024

Cloé Boira, Mohammed Essendoubi, Marie Meunier, Carole Lambert, Daniel Auriol, Michel Manfait, Olivier Piot, Amandine Scandolera, Romain Reynaud

hyaluronic acid Confocal Raman Spectroscopy hair fibers low-molecular weight HA high-molecular weight HA UV-irradiated hair non-irradiated hair hair cortex placebo spontaneous frizzing elastic modulus break force water content cosmetic application HA UV-damaged hair hair strength hair moisture

TLDR Hyaluronic acid in shampoo penetrated hair well, reduced frizz, and improved hair strength and moisture.

The study used Confocal Raman Spectroscopy to investigate the penetration and interaction of Hyaluronic Acid (HA) in hair fibers. The researchers used different shampoo formulations on UV-irradiated and non-irradiated human hair, with low-molecular weight HA, high-molecular weight HA, and a blend of both. The results showed that the HA blend penetrated the hair cortex 5.9 times more than the placebo in non-irradiated samples and 1.8 times more in irradiated samples. The HA blend also significantly decreased spontaneous frizzing by 11%, increased the hair's elastic modulus and break force, and increased the water content in the hair shafts, indicating its potential benefits for cosmetic application.

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Hyaluronic Acid: Elucidating Its Penetration Into and Effect on Hair Fibers Using Confocal Raman Spectroscopy and Biometric Techniques

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