The potential stability of pyrilutamide in a mixture with water, and how it could be used in combination with Minoxidil and Finasteride to treat hair loss.
A user is seeing good results with RU58841 for hair loss, noting reduced shedding and thicker hair. They plan to use pumpkin seed oil as a solvent to avoid watercontent, which they believe reduces the effectiveness of anti-androgens.
The user has been mixing finasteride with stemoxydine for hair loss and is considering switching to a less expensive product with a different ingredient list. They are questioning if the new product's higher watercontent compared to alcohol will affect the finasteride's solubility.
The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.
After 2 years of using finasteride and minoxidil with good results, the user is experiencing severe scalp itchiness, shedding, and tenderness. Despite dermatologists finding nothing wrong, the user seeks over-the-counter treatments for the itch.