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This study found that specific enzymes could be detected in fresh hair sheath cells, with most remaining detectable in older cells, except for Adenylate kinase and Esterase D.

This study demonstrated that de novo designed bifunctional proteins can target and degrade BCL-xL, leading to cell apoptosis, suggesting a new approach to targeted protein degradation therapy.

In this study, proteolytic enzymes applied to mice skin caused severe degeneration in hair follicles, including detachment of stem cells from their niche, suggesting potential impairment of stem cell function.

This study observed that hydrophobic modifications of hair matrix proteins significantly alter the humidity-dependent glass transition temperature of human hair.

This report describes the successful resolution of an epidermoid cyst using a minimally invasive approach with intralesional injection of recombinant enzymes.

This study found that enzymatic phosphorylation of hair keratin increased its capacity to adsorb cationic components like methylene blue and may have practical implications for hair care products.

This study found that permanent wave treatment accelerates hair degradation after protease exposure, showing significant morphological differences compared to untreated hair and linked to damage from Alpha-helical region denaturation.

This study found that an enzymatic method effectively identified chemical treatments like perming and dyeing by detecting higher degradation in treated hair compared to untreated hair.

This study found that treating damaged hair with maleic-modified amino silicone oil created a highly hydrophobic surface, reducing water content and improving hair's mechanical properties and thermal stability.

This study reports that beta-glucan hybrid hydrogels, reinforced with laponite nanoclay, showed promising results in rat models for managing hemorrhage and diabetic wound healing by enhancing hemostasis, reducing inflammation, and promoting faster wound closure and tissue regeneration.

This review discusses the unique properties, design, and fabrication of peptide hydrogels for biomedical applications, focusing on advances in drug delivery, gene therapy, and regenerative medicine; it reports no new clinical results.

This study found that the extraction-resistant structures in hair, feathers, and hagfish teeth are due to ε-(γ-glutamyl)lysine cross-linked proteins, emphasizing their role in maintaining the integrity of these materials.

This study found that biodegradable hyperbranched polyesters improved the solubility and loading capacity of hydrophobic drugs, with complete pyrene release achieved in 16 days under enzymatic conditions.

This research article evaluates the protein content of yeast grown on wood hydrolyzate, without providing new results or clinical findings.

This study used molecular dynamics simulations to illustrate the complex molecular behavior of the hair surface F-layer, highlighting how fatty acids interact with 18-MEA under different conditions.

This study found that at pH 9.0, CYS penetrated less and caused less damage to virgin human hair than TG because it barely reached the cortex region.

This review investigates how the chirality of peptides affects their ability to form hydrogels, comparing the structural and mechanical properties of hydrogels made from homochiral and heterochiral peptides, and discussing their potential biological applications.

This study found that glyoxylic acid caused more protein loss in hair compared to traditional alkaline straighteners, though both types of treatments showed comparable effects on hair tensile strength.

This study used in-silico analyses to investigate papain's potential as a fibrinolytic agent and found that certain fibrin peptides displayed strong interactions with papain, suggesting it may be beneficial for cardiovascular disease treatment.

In this study, extracting internal lipids from Caucasian hair fibers led to decreased water permeability, influenced by the fluidity of lipids.

This study focused on developing agarose/fucoidan hydrogels for the encapsulation of pancreatic cells, reporting that these materials supported cell viability and self-organization into pseudo-islets over 7 days, highlighting potential for diabetes treatment applications.

This study compared hydrolysed wheat protein, L-arginine, and hydrolysed collagen for their effectiveness in enhancing the tensile strength of heavily bleached hair.

This study found that a bio-based repair solution containing hydrolysed wool keratin, serine, and transglutaminase improved the physical and chemical properties of damaged hair, increasing its strength, flexibility, and thermal stability while offering long-lasting protection against chemical damage.

This study found that hair fibers broke down and lost keratin in extremely basic conditions, revealing the inner medulla and changing the color of the fibers.

In this study, cubosome and hexosome carriers with antimicrobial peptides showed varied efficacy, with cubosomes protecting peptides from degradation and enhancing bactericidal effects in some cases, while hexosomes lacked antimicrobial activity.

In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.

In this study, researchers found that L-cysteine interacted electrostatically with anionic ions on the surface of keratin fibers in human hair, reducing the rate of disulfide bond disconnection at pH 9.0.

The researchers reported that applying proteolytic enzymes to mice skin negatively affected hair follicles, leading to degeneration and potential impairment of stem cells from the bulge area.

The researchers reported that hydrogels made from methacrylated glycol chitosan and hyaluronic acid with chondroitin sulfate may be suitable for load bearing soft tissue repair, showing enhanced chondrocyte viability and metabolic activity.