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Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Choosing the right patients, using proper techniques, and having thorough knowledge are key to preventing and managing dermal filler complications.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

New nanocomposites with copper show promise for healing burn wounds and regenerating skin.

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Nanoparticle systems make cancer treatment less toxic.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.

PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.