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Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.

Genetic variations affecting skin structure play a key role in severe acne.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

MALDI Imaging Mass Spectrometry is a useful method for studying skin conditions, but sample preparation is crucial for accurate results.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Platelet-rich plasma therapy may help treat folliculitis decalvans but benefits might not last without ongoing treatment.

Topical vitamin D is effective in treating vitiligo with few side effects.

A man's gray hair got darker and thicker after using a psoriasis drug.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Wnt signaling is crucial for skin wound healing and reducing scars.

Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

Depression and skin autoimmune diseases are linked, needing combined care for better treatment.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.

New digital tools are improving the diagnosis and understanding of irreversible hair loss conditions.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Skin fat plays a key role in immune defense and healing beyond just storing energy.