8 citations
,
June 2022 in “International Journal of Molecular Sciences” This review discusses the potential of extracellular vesicles for facial aesthetic applications, including scar reduction and skin rejuvenation, but reports no new clinical results; further research into production and mechanisms is needed.
7 citations
,
June 2022 in “Frontiers in Medicine” This review discusses the potential of adipose-derived stem cell extracellular vesicles (ADSC-EVs) in skin regeneration, highlighting mechanisms like inflammation and angiogenesis, but reports no new clinical results; challenges and future prospects are also considered.
6 citations
,
June 2022 in “Dermatologic Therapy” This review discusses the biological effects of honokiol for treating skin diseases and reports no new clinical results; the authors recommend further exploration of topical applications.
4 citations
,
October 2022 in “Cell Reports Physical Science” This study developed a novel mineralization strategy using metal-polyphenol coordination for dynamic control of nano-scale processes, enhancing hydrogels that support wound healing with antibacterial and angiogenesis-promoting properties.
3 citations
,
September 2023 in “Skin research and technology” This review article highlights the potential of mesenchymal stem cells, their exosomes, and non-coding RNAs in repairing aging skin tissues due to their ability to secrete beneficial compounds, suggesting their promising role in photoaging treatment without causing immune rejection or granuloma formation.
3 citations
,
January 2023 in “International Journal of Molecular Sciences” This review summarizes current knowledge on the role of heat shock proteins in the pathogenesis of PCOS and their potential implications in developing new treatment strategies, but it reports no new experimental results.
2 citations
,
November 2025 in “Cells” This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.
2 citations
,
January 2023 in “Applied Science and Convergence Technology” This review discusses the potential of 3D bioprinting technologies for tissue regeneration, drug evaluation, and drug delivery systems, but reports no new findings.
March 2026 in “Pharmaceutical Biology” This review discusses the potential of asiaticoside from Centella asiatica for enhancing wound healing after endoscopic submucosal dissection and highlights delivery strategies to improve its gastrointestinal application; it reports no new clinical results.
February 2026 in “International Journal of Molecular Sciences” This review discusses the potential benefits of hyperthermia in cancer therapy, combined with natural compounds, to enhance treatment efficacy and reports no new clinical results.
January 2026 in “Burns & Trauma” This study reported that NLRP3 plays complex roles in wound healing by initially promoting inflammation and delaying repair, but later enhancing structural restoration through distinct signaling pathways, highlighting its potential as a therapeutic target for controlling inflammation and regeneration phases.
October 2025 in “Bioactive Materials” This review highlights the potential of microneedle technology in traditional Chinese medicine as a promising transdermal delivery system for skin diseases, showcasing improved efficacy and reduced side effects of TCM ingredients while discussing the challenges of its clinical application.
July 2025 in “Burns & Trauma” In this study, researchers developed a new SFL-3D system to produce extracellular vesicles from rejuvenated dermal papilla cell spheroids, which demonstrated significant antifibrotic effects in reducing hypertrophic scarring, highlighting their potential for precision-targeted scar management.
April 2024 in “Biomolecules” This review summarizes recent findings on the role of mesenchymal stem cell-derived exosomal microRNAs in skin regeneration and rejuvenation, discussing their potential for treating skin damage and aging, and exploring bioengineering methods to enhance therapeutic effects.
May 2022 in “Frontiers in Cell and Developmental Biology” This study identified that in pig embryos, the miR-29a-5p/EDAR/lncRNA627.1 ceRNA complex plays a critical role in inhibiting hair placode precursor cells proliferation and regulating hair placode formation through the suppression of EDAR expression, which may provide insights into similar mechanisms affecting human hair conditions.
71 citations
,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study presents a novel in vitro assay using human folliculoid microspheres to research hair growth, which may facilitate preclinical testing of hair growth-modulatory agents.
December 2022 in “American journal of medical genetics. Part A” This case report describes an instance of autosomal recessive uncombable hair syndrome caused by maternal uniparental disomy of chromosome 1.
21 citations
,
August 2017 in “Journal of veterinary internal medicine” The authors reported that a combination of amino acid and stem cell therapy may have extended survival in a dog with hepatocutaneous syndrome to 32 months post-diagnosis.
5 citations
,
March 2005 in “Pediatric dermatology” Keratosis Follicularis Spinulosa Decalvans is a rare genetic disorder causing skin and hair issues, often inherited through the X chromosome.
May 2021 in “Journal of the Endocrine Society” This report presents a rare case of suspected 3β HSD deficiency in an adult female with symptoms like male pattern hair loss and low testosterone, suggesting a non-classical presentation.
21 citations
,
January 2018 in “Anticancer Research” This study suggests that NBCCS and BFHS may be the same genetic condition, which could help improve identification and management of misdiagnosed cases with specific surveillance strategies.
6 citations
,
January 2017 in “British Journal of Dermatology” This article reviews frontal fibrosing alopecia, exploring its characteristics, demographics, and associated conditions, and calls for controlled trials due to an increase in worldwide cases; it reports no new findings.
5 citations
,
March 2023 in “Archives of dermatological research” This study found that hidradenitis suppurativa is associated with increased serum levels of hypoxia-inducible factor-1α, suggesting its role in the disease's pathogenesis and as a treatment target.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that impaired Nrf2 signaling and its relationship with keratin 16 may contribute to follicular hyperkeratinization and occlusion in hidradenitis suppurativa, opening new therapeutic avenues.
March 1996 in “Hair transplant forum international” This article discusses the formation and goals of the World Association of Hair Replacement Surgeons, focusing on the exchange of advanced hair restoration surgery techniques, without presenting new research findings.
January 1995 in “Hair transplant forum international” This article argues that a proposed merger between ISHRS and AACS would be detrimental to the ISHRS, but it presents no new research findings.
10 citations
,
November 2015 in “Plant Foods for Human Nutrition” This study found that the ethyl acetate fraction of Hibiscus rosa sinensis petals significantly reduced serum glucose and glycated hemoglobin levels in diabetic rats, showing effects comparable to the standard drug metformin.
June 2022 in “Dermatologic Therapy” This case report describes a 14-year-old girl with congenital hypotrichosis who experienced improved hair density and thickness after 3 months of treatment with oral minoxidil.
January 2015 in “Hair transplant forum international” This snippet mentions an increase in women seeking surgical hair restoration and subsequently encountering more cases of frontal fibrosing alopecia, but the abstract doesn't contain results or conclusions.
In this case report, a 35-year-old woman was diagnosed with Sheehan's syndrome years after severe postpartum hemorrhage, leading to multiple hormonal deficiencies, highlighting delayed diagnosis's impact on treatment and quality of life.