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Older skin has higher cancer risk due to inflammation and stem cell issues.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Genes and hormones cause hair loss, with four genes contributing equally.

Insulin resistance linked to obesity may increase COVID-19 severity.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

The new skin patch with human matrix and antibiotic improves wound healing.

The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

New alopecia treatments aim for better results and fewer side effects.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.