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This study found that the transcription factors Msx2 and Foxn1 are crucial for maintaining Notch1 expression in the hair follicle matrix, which is necessary for proper hair differentiation.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

This study found that prostaglandin metabolism enzymes are present in human hair follicles, suggesting a potential role in hair growth and differentiation, with some expression differences between men and women.

In this study, blocking the CXCR3 receptor in mice prevented the development of alopecia areata by inhibiting the accumulation of specific T cells in the skin, suggesting a potential therapeutic approach for humans.

In this study, topical application of fibroblast growth factors was found to promote hair growth by inducing and prolonging the anagen phase in telogenic C57BL/6 mice, suggesting potential as hair growth-promoting agents.

This study found that overexpression of Wnt1a in bone marrow mesenchymal stem cells enhanced mouse hair follicle regeneration and promoted hair cycling.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

This study found that disrupting inflammasome signaling by eliminating caspase-1 and -11 in mice reduced skin inflammation and delayed the onset of disease, highlighting their role in skin disease pathogenesis.

This study found that testosterone and 5α-dihydrotestosterone induced apoptosis in dermal papilla cells from nonbalding scalp regions, suggesting a high androgen stimulus can trigger cell death related to androgenetic alopecia.

This study observed that in hormone-starved prostate cancer cells, the androgen 5alpha-dihydrotestosterone rapidly induces matriptase activation and shedding, which involves androgen receptor signaling and requires both transcription and protein synthesis.

This review discusses the complex interaction between androgens and hair follicle biology, highlighting the need for a better understanding to improve hirsutism treatments, but reports no new results.

This study identified five mutations in the gene LSS in individuals with unexplained hypotrichosis simplex, highlighting a potential role of mislocalized LSS proteins in disrupting hair follicle biology.

In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.

This study found that oxidative damage is present in the mitochondria of PolG mice, which exhibit premature aging-like phenotypes due to mitochondrial dysfunction.

This study found that IGF-1 injections increased hair follicle number and growth phase duration in wild-type mice, suggesting potential for baldness treatment.

In this study, expressing human K16 in the epidermis of K14 null mice prevented early skin blistering but led to age-related anomalies, indicating K16 and K14 have distinct roles despite their sequence similarity.

This study found that impaired autophagy plays a role in sonic hedgehog pathway-induced endometrial fibrosis, suggesting it as a potential target for treating intrauterine adhesion.

In this study, β-catenin overexpression in human hair outer root sheath cells increased the expression of Pitx2, which activated the follicular differentiation pathway, suggesting Pitx2's potential role as a modulator in hair growth control.

This review examines the role of steroidal inhibitors in treating prostatic diseases but presents no new clinical results.

This study found that the antiandrogen drug enzalutamide reduced TMPRSS2 levels and significantly decreased SARS-CoV-2 entry and infection in lung cells, supporting further clinical trials for COVID-19 treatment.

This study found that four days of simulated night shift work in healthy adults reduced insulin sensitivity, suggesting a potential increased risk of type 2 diabetes.

In this study, red ginseng extract and its ginsenosides enhanced human hair follicle cell proliferation and countered dihydrotestosterone-induced suppression, suggesting potential to promote hair growth.

In a study on muscle regeneration in mice, researchers found that platelet-secreted CXCL7 is crucial for recruiting neutrophils to injury sites, aiding early muscle repair and optimal regrowth, suggesting potential therapeutic uses for boosting muscle healing.

This study reports the creation of rat liver stem cell lines that can differentiate into hepatocytes and suggests they might be useful for pharmacological and regenerative medicine applications.

This study demonstrated effective delivery of CRISPR/Cas9 components to dermal papilla cells in androgenic alopecia animals using ultrasound-activated nanoparticles, resulting in specific gene editing and hair growth recovery.

This study found that polyamines enhance genome integrity by facilitating homologous recombination-mediated DNA repair, suggesting a novel role for polyamines beyond promoting cell growth and proliferation.

This study found that mutations in phosphorylation sites on the PIN3 protein disrupt its phosphorylation and subcellular trafficking, affecting auxin transport and root growth in a cell-type-specific manner.

This review summarizes existing studies on sorafenib, noting its promising effects in some cancers, but also highlights its limitations and potential synergy when combined with other anticancer treatments.

This study found that the Wnt/β-catenin signaling pathway activates melanocyte stem cells, promoting hair follicle regeneration both in vitro and in vivo.

This study reported significant upregulation and release of S100A4 in psoriatic skin, which may actively contribute to psoriasis pathogenesis.