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480-510 / 1000+ resultsresearch Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: effects on keratinocytes, hair and skin
This study found that although progerin expression in mouse skin causes significant nuclear shape changes in keratinocytes, it does not result in alopecia or common skin abnormalities seen in human Hutchinson–Gilford progeria syndrome.
research Steroid 17-Hydroxyprogesterone in Hair Is a Potential Long-Term Biomarker of Androgen Control in Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
This study shows that measuring 17-hydroxyprogesterone concentrations in scalp hair may be a useful noninvasive tool for monitoring treatment in adults with congenital adrenal hyperplasia.
research The Diagnosis and Management of Hirsutism
This review covers the pathophysiology, diagnosis, evaluation, and treatment of hirsutism and reports no new clinical findings.
research Histopathology of Hypotrichosis with Juvenile Macular Dystrophy
In this study, scalp biopsies from HJMD patients revealed histological similarities to chronic telogen effluvium and highlighted the role of CDH3 mutations disrupting normal hair cycles.
research The SAHA Syndrome
This article reviews the characteristics and classification of SAHA syndrome and its relationship with other conditions, without presenting new clinical findings.
research Commentary on: Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis
This study observed that putrescine and HR form a negative feedback mechanism affecting hair cycling, indicating a significant connection between HR, polyamines, and hair growth regulation.
research Hirsutism: Diagnosis and management
This review discusses the causes, clinical features, diagnostic approach, and treatment options for hirsutism in women, but reports no new findings.
research Pruritic urticarial papules and plaques of pregnancy
This case report describes a rare instance of pruritic urticarial papules and plaques of pregnancy in a 25-year-old caucasian primigravida during the third trimester, discussing management recommendations.
research OsPHR2 Is Involved in Phosphate-Starvation Signaling and Excessive Phosphate Accumulation in Shoots of Plants
This study found that overexpression of OsPHR2 in rice leads to increased phosphate accumulation and root architecture changes even under phosphate-sufficient conditions.
research The Follicular Skin Microbiome in Patients With Hidradenitis Suppurativa and Healthy Controls
This study found that the skin microbiome in patients with hidradenitis suppurativa differs significantly from healthy controls, suggesting a potential link between microbial imbalance and the disease.
research Detection of human papillomavirus type 56 DNA, belonging to a mucous high-risk group, in hair follicles in the genital area of a woman no longer suffering from viral warts
This study suggests that hair follicles in the genital area may serve as reservoirs for high-risk human papillomaviruses.
research Finasteride in the treatment of hirsutism: new therapeutic perspectives
This study found that finasteride significantly reduced hirsutism scores in women with idiopathic hirsutism and PCOS, despite no changes in serum androgen levels.
research Molecular functional analyses revealed essential roles of HSP90 and lamin A/C in growth, migration, and self-aggregation of dermal papilla cells
This study found that the interaction between heat shock protein 90 and lamin A/C is crucial for the growth, migration, and self-aggregation of dermal papilla cells, suggesting a potential role in alopecia areata mechanisms.
research The MHS Hair Restoration Protocol: A Systems-Biology Integration of Nutritional Support, Microbiome Modulation, and Targeted Topical ECS Therapeutics
This research introduces the MHS Hair Restoration Protocol, which is a comprehensive approach aimed at restoring the hair follicle environment by modulating the gut-microbiome-endocannabinoidome axis and incorporating specific dietary and topical strategies, rather than focusing only on short-term hair count improvements.
research The benefits of finasteride for hirsute women with polycystic ovary syndrome or idiopathic hirsutism
This study found that finasteride treatment significantly reduced hirsutism and dihydrotestosterone levels in women with idiopathic hirsutism or polycystic ovary syndrome over six months.
research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro
This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.
research Dose‐response of human follicles during laser‐based hair removal: Ex vivo photoepilation model with classification system embracing morphological and histological features
This study found that human hair follicles demonstrated a dose-dependent response to light in an ex vivo photoepilation model, which could predict the clinical efficacy and permanency of light-based hair removal devices.
research 41176 Psoriasis And Mental Health Comorbidities: A Multinational Analysis Using the Global Healthcare Study on Psoriasis (GHSP)
research Factors influencing postoperative hyperesthesia in hair restoration surgery
In this study, researchers found that patients who previously had hair restoration surgery by a different surgeon were more likely to experience postoperative hyperesthesia.
research Hidradenitis suppurativa treated with finasteride
This preliminary study suggests that finasteride may be an effective treatment option for patients with hidradenitis suppurativa, as six out of seven participants showed significant improvement.
research LB821 Human hair follicle dermal papilla as an in vitro model to study stress-induced hair growth arrest
This study highlights that stress-induced activation of the HPA axis in human hair follicles can lead to hair growth arrest, but variability in follicle response complicates potential therapeutic approaches.
research Grading of Hirsutism in Females: A Pilot Study
In this study, researchers evaluated hirsutism in young females aged 18-24 using the modified Ferriman-Gallwey scoring system, finding that 52% showed mild to moderate-to-severe symptoms, often linked to menstrual irregularities and underlying endocrine disorders like polycystic ovary syndrome and thyroid issues.
research ANALÝZA KORTIZOLU VO VLASOCH – BIOMARKER AKTIVÁCIE HPA OSI
This study reported that analyzing hair cortisol levels using a validated online SPE LC-MS method provided a way to assess long-term hormone secretion in 114 healthy volunteers, with a median hair cortisol value of 4.76 pg/mg.
research Dosimetric analysis of the alopecia preventing effect of hippocampus sparing whole brain radiation therapy
This study found that hippocampus sparing whole brain radiation therapy (HS-WBRT) using multi-field intensity modulated radiation therapy prevents alopecia without compromising cognitive function compared to traditional whole brain radiation therapy.
research Helicobacter pylori infection and polycystic ovary syndrome in adolescent and young adult patients
This study found no significant association between Helicobacter pylori infection and polycystic ovary syndrome in young women, suggesting more research is needed to explore a potential link.
research Endoplasmic reticulum stress at the crossroads of progeria and atherosclerosis
This paper reviews the role of endoplasmic reticulum stress and the unfolded protein response in Hutchinson-Gilford progeria syndrome-related atherosclerosis, especially in vascular smooth muscle cells, but reports no clinical findings; intervention in these pathways is suggested as a potential therapeutic strategy.
research Discovery of HAP Stem Cells
This study identified a population of GFP-expressing nestin-positive cells in transgenic mice hair follicles that varied in location during different hair cycle phases, suggesting a shared relationship with neural stem cells.
research Clinical and Investigative Study of Hirsutism
This study found that idiopathic hirsutism was the most common cause of hirsutism among patients, and insulin resistance was significant in those with Hyperandrogenic Insulin Resistant Acanthosis Nigricans Syndrome.
research 215. Plasma testosterone and dihydrotestosterone in cryptorchid boys treated with HCG
This review discusses the antimicrobial and protective effects of hesperidin and hesperetin against various toxicities, with potential mechanisms explored, but it reports no new research findings.