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In this study, TRPV1 signaling was found to play a critical, previously unrecognized role in human sebocyte biology, and targeting this pathway may offer a new approach for managing inflammatory sebaceous gland disorders like acne.

This study concluded that mixtures of weak endocrine disruptors, such as parabens and azole fungicides, can produce combination effects that should be considered in regulatory risk assessments to avoid underestimating potential risks.

In this study, researchers analyzed the waters of Ladakh's hotsprings, identifying 27 bioactive compounds with potential health benefits, but emphasize that further clinical trials are needed to confirm their therapeutic efficacy and safety.

This study surveyed individuals seeking estrogen-based gender-affirming hormone therapy, revealing that improving life satisfaction and femininity are top treatment goals, and highlighting the need for trials aligned with community priorities.

Reduced AhR signaling in HS tunnels leads to persistent inflammation and microbial imbalance.

This research found that nod factor can induce root hair reorientation and gene expression in Medicago truncatula with as little as a single molecule, implicating heterotrimeric G-protein signaling in this process.

In this study, researchers observed that testicular 17β-hydroxysteroid dehydrogenase deficiency in an inbred Arab population in Israel leads to genital ambiguity at birth and progressive virilization after puberty.

This study aimed to investigate the effects of antioxidant therapy on skin aging in MetS patients in Latvia but provides no new findings on its effectiveness.

This study identified that spermidine-mediated activation of eIF5A by hypusination plays a significant role in Arabidopsis thaliana growth, flowering time, stress adaptation, and development, including changing root and aerial architecture.

This study found that applying the highest dose of biostimulant improved the fresh yield, leaf area, and ACO2 of hydroponically grown ‘Genovese’ basil, suggesting enhanced productivity with reduced fertilizer use.

This article reviews the limited evidence on testosterone therapy for premenopausal women and notes a lack of long-term safety and effectiveness data for this population.

This study found that spraying melon plants with 0.1 mg·L–1 molybdenum significantly improved growth, photosynthetic characteristics, carbohydrate metabolism, and fruit quality under high-temperature stress, boosting fruit weight by 27.9% and yield per plant by 20.1% compared to untreated controls.

This article reviews the growing interest and potential health benefits of nutraceuticals, especially herbal products, highlighting their role in maintaining health, preventing diseases, and improving quality of life, while also discussing developments in nutraceutical research and challenges related to aging skin.

This review examines the molecular effects of photobiomodulation therapy, particularly its influence on gene and protein expression related to inflammation and cell functions, but reports no new clinical results.

This review discusses nonsteroidal selective androgen receptor modulators and their potential therapeutic applications but reports no new clinical findings.

This study observed that inhibiting androgenic activity during early postnatal development significantly decreased body weight in female rats by day 90, while affecting food intake and fat distribution in both sexes based on the inhibited testosterone metabolic pathway.

This study suggests that Epimedium can serve as a complementary and alternative treatment for chronic bone and joint diseases, potentially laying the groundwork for its clinical application.

In this study, engineered mice with a mutation similar to that in Olmsted syndrome showed progressive hair loss due to impaired inner root sheath keratinocyte differentiation and stem cell exhaustion.

This study presents the design of an autonomous bioregeneration chamber that aims to extend human lifespan to 130-150 years by optimizing biological and environmental conditions, suggesting that a longer healthspan is possible through technological, nutritional, and socio-economic interventions.

This study observed that in spontaneously hypertensive rats, testosterone's effects on endothelium-dependent vasodilation involved reduced nitric oxide levels, increased oxidative stress, and greater reliance on endothelium-dependent hyperpolarization, with variations in these responses noted when testosterone was combined with either anastrozole or finasteride.

This review assessed prior rodent studies on low-dose endocrine toxicity and found no confirmatory evidence, suggesting variability in control groups as a major confounding factor.

Aging weakens sweat glands due to reduced support from immune cells, but treatments may help restore function.

This study demonstrated that metabolomics could identify persistent biomarkers distinguishing between heavy ion and γ radiation exposures, offering a potential tool for assessing long-term radiation risk for intestinal pathologies.

This study describes the enzymatic processes through which DHEA is converted to active sex steroids in human skin, highlighting an androgenic effect on sebaceous glands and estrogenic effects in the vagina.

This article suggests that testosterone therapy might be considered if other treatments fail, but emphasizes discussing potential risks and benefits with patients before prescribing.

This article reviews the therapeutic use of carnitine derivatives for re-establishing mitochondrial functionality in aging and reports no new clinical results.

This study found that topical application of mitochondrial electron transport chain inhibitors stimulated hair follicle stem cell activation and hair regrowth in aged mice by promoting lactate production.

This review discusses the role of androgens in women's sexual health and highlights the need for further research on androgen replacement therapy to optimize quality of life, but reports no new clinical results.

This study found that specialized nipple epidermis in mice is maintained by the repression of TGFβ signaling through estrogen, which highlights the role of hormonal regulation in epidermal maintenance.

This review discusses female androgen insufficiency syndrome and reports no new clinical results; the authors suggest that testosterone replacement may alleviate symptoms like loss of libido and fatigue.