16 citations
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July 2013 in “The American Journal of Dermatopathology” This study observed that pigmented casts are present in various alopecia types but are not specific to any single diagnosis, with distinct morphological features noted in trichotillomania.
April 2012 in “Informa Healthcare eBooks” Temporal triangular alopecia is a lifelong condition with hairless patches on the side of the head that may be present from birth.
33 citations
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August 2005 in “The American Journal of Dermatopathology” This article provides departmental contact information for Dr. Dirk M. Elston at the Geisinger Medical Center and reports no research findings.
71 citations
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March 1995 in “Journal of The American Academy of Dermatology” This study concluded that combining vertical and transverse sections of scalp biopsy specimens improves diagnostic yield for certain hair disorders without increasing costs.
56 citations
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July 2005 in “Journal of The American Academy of Dermatology” This study found that vertical sections of alopecia biopsy specimens had a higher concordance rate with the original combined diagnosis compared to transverse sections alone, although both methods have their pros and cons.
19 citations
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September 2011 in “Clinical and Experimental Dermatology” This study suggests that for single biopsy specimens, transverse sections may be preferable for diagnosing noncicatricial alopecia, while vertical sections may be better for suspected lichen planopilaris.
137 citations
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July 2004 in “Journal of The American Academy of Dermatology” This study observed that triple horizontal scalp biopsies provided a more accurate diagnosis of female pattern hair loss in women than a single horizontal biopsy, especially for those with advanced hair loss.
January 2026 in “Forum Dermatologicum” This study observed that 2.5% of patients with mycosis fungoides or Szary syndrome experienced alopecia, predominantly within skin lesions, with scalp metastases from other cancers also potentially causing hair loss, highlighting the diagnostic value of trichoscopy in differentiating alopecia types.
November 2020 in “Journal of Cosmetic Dermatology” This study conducted in a hair restoration clinic found that using the vertical scalp mobility method resulted in a significantly greater number of hairs available from the donor strip compared to the horizontal method, with an increase of approximately 970 hairs (P < .05).
115 citations
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October 2003 in “Journal of Neuroscience” This study found no evidence supporting the hypothesis that Aβ afferents sprout into the superficial laminas of the spinal cord after nerve injury in rats.
1 citations
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May 2020 in “Journal of The American Academy of Dermatology” This correspondence highlights existing research on pattern hair loss, discussing findings about immune deposits, lymphocytic infiltration, and responses to treatment, and calls for future well-controlled studies.
43 citations
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May 2011 in “Dermatologic Therapy” This article discusses the phases and histological features of alopecia areata and reports no new clinical findings; the authors emphasize recognizing these phases for accurate diagnosis.
6 citations
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March 1999 in “Seminars in Cutaneous Medicine and Surgery” This report presents four cases highlighting diagnostic challenges between specific types of alopecia, comparing their clinical and histopathologic features without providing new research findings.
139 citations
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July 1991 in “Journal of The American Academy of Dermatology” This article discusses the structure of hair follicles and their significance in evaluating hair disorders, but it does not report any new research findings.
3 citations
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January 2019 in “Indian Journal of Dermatology” This study observed that transverse sectioning of scalp biopsies may aid in diagnosing different types of alopecia by revealing distinct histopathological features like follicle miniaturization and specific inflammatory patterns.
January 2024 in “Journal of Natural Remedies” This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.
13 citations
,
March 2021 in “Frontiers in oncology” This review discusses the strong correlation between reflectance confocal microscopy images and horizontal histopathology in diagnosing skin tumors, highlighting the reliability of this non-invasive technique; no new clinical results are reported.
5 citations
,
November 2006 in “Dermatologic Surgery” The researchers reported that pubic hair transplantation surgery may help improve self-esteem in women with pubic atrichosis or hypotrichosis by achieving natural and realistic-looking results.
January 2017 in “International journal of transplantation & plastic surgery” This article reviews the historical development and advancements in hair transplant techniques, from punch grafting in the 1950s to the modern follicular unit extraction, and reports no new clinical results.
11 citations
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August 2025 in “Journal of Periodontal Research” This review highlights that autologous platelet concentrates, particularly platelet-rich fibrin, have shown potential to enhance healing and outcomes in both dental and medical applications, including injury recovery and aesthetics.
2 citations
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January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study on Iranian patients with non-scarring alopecia, researchers found that androgenetic alopecia was the most common subtype, with perifollicular inflammation observed more in males. They reported that transverse sectioning is generally sufficient for diagnosis, but combining with vertical sectioning provides more comprehensive information.
1 citations
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December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses various methods for processing and separating human skin samples for research purposes, evaluating factors like processing time and cell viability, but reports no new experimental findings.
October 2001 in “Dermatologic Surgery” This study found that horizontally bisected donor hairs can be used to create finer hairlines, with about 46-47% growth reported in transplanted hair shafts and bulbs.
93 citations
,
June 2011 in “Journal of Neuroscience” This study found that the transcription factor p63 is crucial for horizontal basal cell differentiation in the olfactory epithelium, suggesting a p63-dependent mechanism activates reserve stem cells after injury.
36 citations
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June 2009 in “Nanomedicine” This study found that fullerene nanomaterials can significantly enhance hair growth and increase hair follicle numbers in both shaved and bald mouse models, as well as in cultured human skin sections.
June 2026 in “Cell Regeneration” This review highlights the roles of key transcription factors and signaling pathways in regulating olfactory epithelium regeneration, discussing recent advances in single-cell and spatial transcriptomics as well as organoid models to enhance understanding of olfactory regeneration mechanisms.
August 2023 in “Journal of the American Academy of Dermatology” A scalp biopsy is essential for accurately diagnosing alopecia, with a 4-mm punch biopsy sectioned horizontally being the recommended technique according to this study.
40 citations
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May 2012 in “British Journal of Dermatology” This study reviewed scalp biopsies from African-American patients, identifying distinct features and diagnostic clues for scarring alopecia types such as traction alopecia and central centrifugal cicatricial alopecia.
42 citations
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December 1990 in “The Journal of Dermatologic Surgery and Oncology” This study found decreased hair density and altered follicular architecture in the balding frontal scalp of patients with androgenic alopecia, with increased vellus hairs noted.
9 citations
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November 2009 in “Journal of the European Academy of Dermatology and Venereology” This study found that serial vertical sectioning of scalp biopsies significantly increases the histological diagnostic yield for alopecias.