309 citations
,
May 1993 in “Journal of The American Academy of Dermatology” This study concluded that horizontal sections of scalp biopsy specimens provide more diagnostic information for male pattern androgenetic alopecia than vertical sections and can predict hair regrowth potential following topical minoxidil therapy.
19 citations
,
December 2001 in “Dermatologic Therapy” This study reports that horizontal sections of scalp biopsies improve the diagnosis of alopecia areata, especially when characteristic inflammatory infiltrates are missing.
12 citations
,
June 2013 in “The American Journal of Dermatopathology” This study reported that using photomnemonics facilitated accurate histopathologic interpretation of horizontal scalp sections in distinguishing between nonscarring and scarring alopecias by dermatopathologists and residents in a validation test.
3 citations
,
January 2018 in “Dermatology” This study found that transverse sections of scalp biopsies, particularly looking at the anagen:non-anagen hair ratio and presence of pigment casts, effectively distinguish alopecia areata from androgenetic alopecia.
11 citations
,
April 2020 in “Journal of The American Academy of Dermatology” This commentary reviews the evidence for microinflammation's role in pattern hair loss and suggests that further studies with age- and sex-matched controls are needed to substantiate the findings.
16 citations
,
February 2018 in “Journal of The American Academy of Dermatology” This study found that scalp involvement in dermatomyositis consistently shows a nonscarring pattern with chronic telogen effluvium, featuring telangiectasia and mucin deposition as universal histologic markers.
29 citations
,
September 2014 in “American Journal of Dermatopathology” This study found that horizontal sections of scalp biopsies in patients with Central Centrifugal Cicatricial Alopecia often reveal follicular miniaturization, inflammation, and scarring, which can guide personalized treatment.
1 citations
,
November 2024 in “Journal of Cutaneous Pathology” This case study reported on a 72-year-old woman initially diagnosed with inflammatory alopecia, later identified as having angiosarcoma of the scalp, revealing the importance of considering unexpected malignancies during evaluation of suspected inflammatory alopecia cases.
January 2018 in “Figshare” This study found that transverse sections of scalp biopsies showing lower anagen:non-anagen hair ratios and presence of pigment casts help differentiate alopecia areata from androgenetic alopecia.
11 citations
,
August 2017 in “American Journal of Dermatopathology” This study found that the Elastic Verhoeff–Van Gieson stain may help differentiate between follicular streamers and scars in cicatricial and noncicatricial alopecias by highlighting differences in the elastic fiber network on horizontal scalp biopsy sections.
145 citations
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December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride 1mg helps reverse hair miniaturization in men and postmenopausal women.
January 2026 in “Skin Appendage Disorders” This study concluded that including intermediate hairs or using relative shaft diameter methods can significantly improve the sensitivity of trichograms in diagnosing female androgenetic alopecia, aligning better with histopathology results.
24 citations
,
August 2005 in “The American Journal of Dermatopathology” This article critically assesses literature favoring horizontal over vertical sections for diagnosing scalp diseases and concludes that a qualitative, vertical approach improves diagnostic precision for alopecias.
54 citations
,
January 2005 in “Journal of The American Academy of Dermatology” In this study, four women with chronic telogen effluvium experienced fluctuating hair shedding without visible reduction in hair density or follicular miniaturization over at least 7 years.
35 citations
,
November 2010 in “Journal of Cutaneous Pathology” This study reported that dilated follicular infundibula are a highly useful histopathologic criterion for diagnosing alopecia areata, particularly during its recovery stage.
14 citations
,
September 2016 in “Journal of Cutaneous Pathology” This review discusses the classification and diagnosis of primary scalp alopecia, focusing on scarring and non-scarring types, and reports no new clinical results; it emphasizes simplified diagnostic pathways and tissue processing techniques.
3 citations
,
November 1999 in “Journal of Cutaneous Medicine and Surgery” Examining scalp biopsies in different ways helps better diagnose hair loss types.
1 citations
,
January 2017 in “Springer eBooks” The document explains how hair follicles develop, their structure, and how they grow.
2 citations
,
July 2013 in “InTech eBooks” This article reviews the differences between scarring and non-scarring alopecias and describes diagnostic methods but reports no new clinical findings.
44 citations
,
January 2011 in “Journal of Cutaneous Pathology” This study introduces the "HoVert" technique, which generates both vertical and horizontal sections from a single biopsy to effectively differentiate lichen planopilaris from discoid lupus erythematosus in alopecia cases.
9 citations
,
June 2008 in “Springer eBooks” Understanding hair follicle structure is key for treating hair disorders and could help develop new treatments.
March 2012 in “Journal of The American Academy of Dermatology” Hair casts are often mistaken for head lice, scalp pain in hair loss is linked to certain nerve factors, eyelash growth treatment is safe and effective, and nail shedding in children may follow hand-foot-mouth disease.
10 citations
,
July 2017 in “Archives of Plastic Surgery” This study found that hair diameter varies significantly within the occipital safe donor area, with thicker hair in the upper sections and thinner hair in the lower sections.
3 citations
,
September 2013 in “Journal of the European Academy of Dermatology and Venereology” This study suggests that using ex vivo dermatoscopy can improve the accuracy of scalp biopsy processing by correctly guiding tissue bisection and potentially reducing laboratory costs and turnaround time.
1 citations
,
August 2016 in “Journal of Buffalo Science” This study examined hair follicle arrangement to identify a suspected wild boar involved in a dynamite blast, concluding based on circumstantial evidence that it may have belonged to a wild boar.
24 citations
,
September 2002 in “Dermatologic Surgery” This study describes the anatomy of arrector pili muscles in scalp hair follicular units, proposing a model where a single muscle structure is shared by all follicles within a unit.
2 citations
,
September 2002 in “Dermatologic Surgery” This study describes how arrector pili muscles form a single muscular structure shared by all hair follicles within a follicular unit at the isthmus level in scalp skin.
1 citations
,
July 2018 in “Elsevier eBooks” This review discusses the basic principles of hair pathology and findings in common types of alopecia but reports no new research results.
5 citations
,
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that by using an automated system to analyze skin histology, 108 structural features were significantly affected by age, and it identified four new aging biomarkers and notable sex-based differences in skin aging.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” The study concluded that a 'Swiss cheese' pattern in hair follicles is a useful sign for diagnosing alopecia areata.