February 2026 in “Cureus” In this narrative review, the authors compared monotherapy and combination therapy for type 2 diabetes, finding that while monotherapy is effective in early stages, combination therapy offers superior glycemic control and cardiovascular benefits, though it requires individualized selection for safety and adherence.
12 citations
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October 2023 in “Journal of Mind and Medical Sciences” This source presents a comprehensive review of the literature on diabetes, highlighting the complex factors involved in its development and the importance of prevention, early diagnosis, and a multi-faceted treatment approach for effective management.
23 citations
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January 2016 in “Frontiers in immunology” This review discusses the potential of combining low-dose IL-2 with islet antigens to enhance antigen-specific Treg function in type 1 diabetes, but reports no new clinical results.
68 citations
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April 2002 in “Journal of Human Nutrition and Dietetics” This study found that although diabetic patients undergoing a very low calorie diet experienced faster weight loss initially, those on a conventional diet and exercise plan maintained weight loss more effectively over five years.
32 citations
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January 2007 in “KARGER eBooks” This review discusses severe insulin resistance syndromes, highlighting their diagnostic challenges, potential novel therapies like leptin replacement, and suggests metformin and lifestyle changes in its absence; no new clinical results are reported.