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The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Skin health and diseases are closely linked to metabolic processes.

Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Zinc levels in body fluids can help diagnose zinc deficiency in lambs, with fecal zinc as an early indicator.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.

Exosomes could improve skin care, but more research is needed to confirm their safety and effectiveness.

Targeting the Smoothened receptor shows promise for treating certain cancers.

New regenerative treatments for hair loss show promise but need more research for confirmation.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Adenosine receptors could be promising targets for treating inflammatory skin diseases like psoriasis.

More precise, personalized therapies are needed for autoimmune diseases.

Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.

Creatine monohydrate is safe and effective for muscle recovery and performance, especially for those with low creatine levels.

Stem-cell therapy shows promise for skin conditions but needs more research.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.