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In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.

This case study describes a 22-year-old woman with hirsutism who experienced symptom reversal through addressing nonclassical adrenal hyperplasia and polycystic ovaries alongside laser hair removal.

This study presents a new method called scMC that effectively distinguishes biological from technical variation in single-cell genomics datasets, demonstrating its ability to accurately align and detect biological signals across various experiments.

This review presents an evidence-based algorithm for managing hidradenitis suppurativa in primary care, highlighting the need for more research on treatment effectiveness and the disease's pathogenesis.

This report describes a novel mutation in the CDH3 gene in an 11-year-old Iranian boy with hypotrichosis and juvenile macular dystrophy, indicating a new genetic variant associated with the disorder.

This review develops expert-guided recommendations for hidradenitis suppurativa management, highlighting evidence for the effectiveness of antibacterial and anti-tumor necrosis factor therapies, but reports no new clinical trial results.

This case report describes a 36-year-old woman with hidradenitis suppurativa whose condition progressed to rapidly fatal squamous cell carcinoma, highlighting the potential for aggressive tumor development linked to specific protein markers.

This case report emphasizes the importance of recognizing non-classic congenital adrenal hyperplasia as a cause of hyperandrogenism and the need for genetic counseling given potential familial implications.

This report details two patients with Hutchinson-Gilford Progeria syndrome who exhibited generalized shiny skin in infancy and had a novel mutation in the LMNA gene.

This review discusses the causes and management of hirsutism and suggests improvement can be achieved with a combination of hair removal, suppression of androgen production, and lifestyle changes over 6 to 9 months.

This study found that SHJH hr mice, with a Hairless gene mutation, exhibit accelerated skin aging potentially due to poor antioxidative protection, highlighting the Hr gene's role in skin aging.

This study found that serum-free expanded hair follicle mesenchymal stem cells (hfMSCs), derived from hair plucking, significantly improved cartilage repair in a murine model despite minimal engraftment, suggesting their effectiveness through a paracrine mechanism.

In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.

This study identified a novel heterozygous missense mutation in the hHb3 gene associated with monilethrix, highlighting its role in this hair disorder.

This study found that high-flux hemodialysis combined with L-carnitine improved heart function, reduced inflammation, and decreased venous fistula complications in maintenance hemodialysis patients.

This article provides an overview of treatment options for hirsutism, summarizing both pharmacologic and non-pharmacologic approaches, but reports no new clinical results.

This study found that using PRP injections in skin flap reconstructions and combining acellular dermal matrix with split-thickness skin grafts improved healing and reduced complications in the surgical treatment of hidradenitis suppurativa.

This report announces that the International Society of Hair Restoration Surgery received Accreditation with Commendation.

This paper reviews how studying the microbiome of the freshwater polyp Hydra can inform new, microbiome-targeting therapies for human hair follicle and skin diseases; it presents no new experimental findings.

This article discusses the introduction of human recombinant hyaluronidase in hair restoration surgery and presents no new clinical results.

This article reviews idiopathic hirsutism, focusing on its definition, diagnosis, causes, and treatment options, without presenting new clinical findings.

PRO-C22 can help diagnose and monitor the severity of hidradenitis suppurativa.

This study describes new devices, "HairMeasure" and "Scalp Zone Identifier," which offer an economical method to calculate Hair Mass Index without disposable materials.

In this study, hair follicle-derived mesenchymal stromal cells showed potential for immunomodulation, with equivalent or superior responses compared to those from adipose tissue, suggesting a promising alternative cell source.

In this study, the authors developed a medicated face mask using electrospun fibers to deliver the active compound Eflornithine hydrochloride for managing hirsutism. The mask showed promising drug release characteristics, a high safety profile, and reduced hair growth in mice.

This study identified two novel point mutations in the hHb6 gene associated with monilethrix, suggesting these mutations could serve as diagnostic markers for this genetic hair disorder.

This study found that the hairless gene in mice has a more extensive role in development than previously thought, as indicated by its expression in various tissues and associated abnormalities in hr/hr mutants.

This review examines hydrogel microneedles for transdermal drug delivery, discussing their applications and challenges but reports no new clinical results.

This study found that hippocampus sparing whole brain radiation therapy (HS-WBRT) using multi-field intensity modulated radiation therapy prevents alopecia without compromising cognitive function compared to traditional whole brain radiation therapy.

This case report suggests that human dermal papillae conditioned media may accelerate wound healing in congenital aplasia cutis due to varicella infection.