February 2024 in “Skin research and technology” The researchers in this study identified molecular mechanisms involved in frontal fibrosis alopecia, highlighting immune response and fatty acid metabolism, and developed a four-gene diagnostic model showing high accuracy in distinguishing affected individuals from controls.
June 2023 in “Frontiers in Medicine” This study identified core genes and pathways involved in androgenetic alopecia, finding that genes related to hair follicle development are down-regulated, while those linked to immune responses are up-regulated, highlighting potential therapeutic targets.
June 2021 in “Journal of The American Academy of Dermatology” This study suggests that the "spade sign" is a highly specific histopathologic feature of acne keloidalis, although its absence does not rule out the condition.
December 2020 in “Nigerian journal of animal production” This study found that dexamethasone may induce diabetes in albino rats and Annona muricata methanolic bark extract resulted in significantly reduced blood sugar levels in dexamethasone-induced diabetic rats.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study demonstrated that prevascularized human skin constructs containing engineered hair follicles can successfully induce human hair growth when grafted onto mice by promoting blood supply to the grafted skin.
April 2018 in “Journal of Investigative Dermatology” In this study, injecting Fetuin A into embryonic mouse wounds led to scar formation, suggesting the protein may play a role in scar development by promoting collagen production.
October 2017 in “Springer eBooks” A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.
August 2017 in “Companion animal” This article discusses the diagnostic approach to focal alopecia in dogs, focusing on distinguishing between pruritic skin disease and inflammatory or non-inflammatory causes; it presents no new experimental results.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Quantitative Mass Spectrometry Imaging offers precise localization and quantification of active compounds in skin tissues, demonstrating benefits over traditional LC-MS in drug penetration studies.
April 2017 in “Journal of Investigative Dermatology” In this study, researchers demonstrated that the Id2 gene acts as a direct target and effector of BMP signaling, playing a key role in maintaining quiescence in hair follicle stem cells in vivo.
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study concluded that a new model of reconstructed human epidermis using keratinocytes from plucked hair follicles offers a less-invasive alternative to conventional skin-derived models for skin research.
January 2015 in “Hair therapy & transplantation” This review updates on various methods for hair and scalp examination, encompassing non-invasive, semi-invasive, and invasive techniques, and reports no new results.
February 2008 in “Basic and clinical dermatology” Photographic imaging is crucial for documenting and managing hair loss, requiring careful preparation and standardization to be effective.
January 2009 in “Egyptian Journal of Medical Human Genetics” This study, conducted among Egyptians, found a borderline significant association between the Stul polymorphism of the androgen receptor gene and androgenetic alopecia in males, with higher androgen receptor expression in balding scalp areas.
140 citations
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December 1998 in “Journal of Investigative Dermatology” Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.
13 citations
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September 2022 in “Biomolecules” This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.
8 citations
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July 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified four circulating microRNAs as highly predictive of frontal fibrosing alopecia status, suggesting potential roles in diagnostics and disease understanding.
7 citations
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February 2022 in “Frontiers in Medicine” This study found that combining microneedling with PRP was more effective than microneedling alone for improving acne scars, with higher patient satisfaction and no significant increase in severe side effects.
2 citations
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September 2024 in “Journal of the American Academy of Dermatology” CCCA in African Americans may be linked to hair grooming, low vitamin D, and autoimmune factors.
1 citations
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November 2024 in “Journal of Cutaneous Pathology” This case study reported on a 72-year-old woman initially diagnosed with inflammatory alopecia, later identified as having angiosarcoma of the scalp, revealing the importance of considering unexpected malignancies during evaluation of suspected inflammatory alopecia cases.
March 2026 in “Applied Sciences” In this scoping review, researchers observed that while AI-assisted trichoscopy holds promise for standardized assessments of hair and scalp disorders, its clinical translation is limited by small proprietary datasets, inconsistent validation protocols, and a scarcity of real-world clinical studies.
March 2023 in “Nigerian Journal of Clinical Practice” This study found that SLE patients with hair loss exhibited significant differences in the size and number of sebaceous glands compared to those without hair loss, but showed no histopathological differences between affected and unaffected scalp areas.
January 2022 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This article presents an overview of uncombable hair syndrome, emphasizing its clinical and molecular characteristics and noting systemic manifestations such as neuropsychiatric, ophthalmic, and cardiopulmonary issues.
3 citations
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April 2016 in “Food Science and Biotechnology” This study found that Oriental melon leaf extracts promoted hair growth in a mouse model and cultured human hair follicles, suggesting potential use as a treatment for hair loss.
January 2025 in “International Journal of Veterinary Science” In this animal study, hibiscus leaf simplicia ointment was found to protect red blood cell levels and promote better hair growth in UV-exposed rats, though it did not maintain normal skin histology; the ointment showed no significant acute dermal toxicity.
January 2025 in “BMC Genomics” In this study, researchers identified thousands of mRNA, lncRNA, circRNA, and miRNA transcripts involved in different hair follicle stages of Rex rabbits and highlighted significant gene expression changes and pathway enrichments, providing insights into the regulatory mechanisms of hair development in these animals.
835 citations
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October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
137 citations
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December 2006 in “Arthritis Research & Therapy” This study found that mycophenolate mofetil was associated with higher response rates and lower rates of serious side effects, including a lower mortality rate, compared to cyclophosphamide in lupus nephritis treatment.
122 citations
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June 2002 in “Genes & Development” This study found that K17 is crucial for the structural integrity and survival of hair-producing cells, with K17 null mice developing alopecia due to hair fragility and follicular alterations.
117 citations
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August 1999 in “Nature Genetics”