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180-210 / 1000+ resultsresearch Regeneration Genetics
This review discusses recent genetic approaches to understanding tissue regeneration mechanisms in vertebrates and reports no new results; it highlights objectives in identifying cellular and molecular factors involved.
research Anatomy and Biology of Hair at Different Ages
This study explored the complex developmental processes of human hair, emphasizing the intricate interactions required for hair follicle morphogenesis and its implications for drug incorporation and concentration interpretation, particularly in early childhood.
research Molecular Mechanisms of Hair Follicle Development
This paper reviews the molecular mechanisms involved in hair follicle development, highlighting their potential impact on human health and well-being, and discusses advancements in treating hair loss, enhancing wound healing, and developing cosmetic treatments.
research Author response: Coordinated hedgehog signaling induces new hair follicles in adult skin
In this study, activation of Hedgehog signaling in both epithelial and stromal cells induced new hair follicles in adult mouse skin, but also resulted in the formation of tumors.
research Decision letter: Coordinated hedgehog signaling induces new hair follicles in adult skin
This study found that activating Hedgehog signaling in both epithelial and stromal cells can induce new hair follicles in adult mice, but this also leads to tumor formation.
research [Hair physiology].
This article describes the development and growth stages of hair follicles during intrauterine life and subsequent growth phases on the scalp but reports no new clinical results.
research Critical Stages of Hair Development and Pigmentation in the Mouse
Hair growth and pigmentation in mice involve specific stages crucial for research.
research Endogenous human skin equivalent promotes in vitro morphogenesis of follicle-like structures
This study demonstrated that an engineered human skin equivalent can generate follicle-like structures resembling fetal skin, highlighting the role of the dermal compartment in directing epithelial cell fate in vitro.
research From Follicle Cell Differentiation and Structure to Chorion Biogenesis in Insects: Cellular Mechanisms, Gene Regulation, Biochemical Composition and Structural Diversity
This review synthesizes current knowledge on choriogenesis, the final stage of oogenesis in insects, by exploring the role of follicle cells, regulatory mechanisms of gene expression, and the biochemical makeup of the eggshell, while also highlighting structural diversity and adaptations across insect species.
research Hierarchical patterning modes orchestrate hair follicle morphogenesis
This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.
research Parallels in signaling between development and regeneration in ectodermal organs
research Molecular Signaling Pathways in Wound-Induced Hair-Follicle Neogenesis
This review discusses the mechanisms regulating wound-induced hair-follicle neogenesis and highlights potential treatments, like Wnt signaling activators, for enhancing this process in humans, yet reports no new clinical results.
research Growth Factor and Growth Factor Receptor Localization in the Hair Follicle Bulge and Associated Tissue in Human Fetus
research Hair Follicle Pluripotent Stem (hfPS) Cells
research 0140 Delineating key molecular programs that induce hair-follicle-inductive dermal fibroblasts using a novel single-cell genomic approach
Wnt and SHH pathways help form hair follicles by coordinating cell processes.
research Keloid pathogenesis and fibroproliferative properties are dependent on stem cells regulated by the HEDGEHOG-GLI1 pathway
This study observed that the Hedgehog-GLI1 signaling pathway is upregulated in keloid patient–derived stem cells, and inhibiting this pathway reduced keloid characteristics in both mice and ex vivo tissue cultures, suggesting potential therapeutic targets for keloid treatment.
research Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
This study found that activating the Sonic hedgehog pathway in scarring wounds can remodel the dermis to promote hair follicle regeneration, highlighting a potential new approach to enhance healing.
research Hox in hair growth and development
research May the best wound WIHN: the hallmarks of wound-induced hair neogenesis
This review discusses recent advancements in Wound Induced Hair Neogenesis in mice, emphasizing the potential of neogenic hair regeneration to enhance understanding of adult mammalian regeneration, but reports no new experimental results.
research Inducing hair follicle organogenesis with defined environmental protein factors
This study found that protein extracts from embryonic skin can induce hair follicle neogenesis in mice by activating insulin/IGF signaling in adult fibroblasts.
research A family business: stem cell progeny join the niche to regulate homeostasis
This review discusses the role of stem cell progeny as integral components of stem cell niches, offering feedback that may influence different stem cell systems' microenvironments, but it presents no new research findings.
research Contrastive Rhetoric: Development and Challenges
This review discusses the cellular and molecular basis of wound-induced hair neogenesis and its age-related changes, reporting no new clinical results but highlighting areas for future research.
research Organ Regeneration
This book reviews organogenesis in developmental biology and next-generation organ regenerative therapy but reports no new research findings.
research Kinetics of blood cell differentiation during hematopoiesis revealed by quantitative long-term live imaging
This study reports that fly blood progenitors in a long-term organ culture model undergo symmetric cell divisions influenced by cell size and orientation, with infection triggering changes in cell differentiation kinetics.
research Hair follicle stem cell progeny heal blisters while pausing skin development
In this study, researchers found that in growing skin tissue, epidermal wound healing occurs at the expense of normal skin development, as it impairs hair follicle growth and does not activate tissue morphogenesis genes.
research The Role of the Hairless (hr) Gene in the. Regulation of Hair Follicle Catagen Transformation
This study found that the loss of a functional hr gene in mice leads to premature and abnormal hair follicle regression, disrupting normal hair cycling and architecture.
research Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis
This study demonstrated that fibrin hydrogels support skin-derived precursors in hair follicle neogenesis in mice, with new hair growth and regeneration of blood vessels and sebaceous glands observed.
research The walking dead: sequential nuclear and organelle destruction during hair development
This study revealed that hair cells undergo an organized process to become keratin-packed "zombie" cells, highlighting a key area for treatment development in the first 1mm of hair follicles.
research Organ regeneration based on developmental biology: past and future
This review discusses recent advancements in regenerative medicine, including functional organ regeneration and the creation of mini-organs, and reports no new clinical results.