research Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men
Finasteride can cause sexual problems and depression in young men.
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research Consensus on the Use of Oral Isotretinoin in Dermatology - Brazilian Society of Dermatology
The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.
research Minoxidil Prevents MDMA-Induced Serotonin Depletions: Role of Mitochondrial ATP-Sensitive Potassium Channels, Akt, and ERK
Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.
research Roles of Steroid Sulfatase in Brain and Other Tissues
Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
research Finasteride Adverse Effects in Subjects with Androgenic Alopecia: A Possible Therapeutic Approach According to the Lateralization Process of the Brain
Finasteride may cause mental and sexual side effects, with hand preference and sexual orientation possibly affecting severity.
research Long-Term Control of Epileptic Drop Attacks With the Combination of Valproate, Lamotrigine, and a Benzodiazepine: A Proof of Concept, Open Label Study
The drug combination significantly reduced epileptic drop attacks in patients.
research The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli
Finasteride reduces response to stress and rewards, affecting behavior and mental health.
research Cognitive and Mood Side Effects of Lower Urinary Tract Medication
Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.
research Immediate and Delayed Complications of Dexamethasone Cyclophosphamide Pulse Therapy
DCP therapy causes side effects like weakness, flushing, headaches, and taste changes, but less frequently causes hypertension and diabetes.
research Repeated Finasteride Administration Induces Depression-Like Behavior in Adult Male Rats
Finasteride use can cause depression-like behavior in male rats.
research Persistent Sexual Dysfunction with Finasteride 1 mg Taken for Hair Loss
Finasteride for hair loss increases risk of long-lasting sexual dysfunction.
research Relating Neurosteroid Modulation of Inhibitory Neurotransmission to Behavior
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research Alterations of Gut Microbiota Composition in Post-Finasteride Patients: A Pilot Study
Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
research Phytochemical, Toxicological and Pharmacological Studies of Asiasari Radix et Rhizoma: A Review
Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.
research TSPO Activation Modulates the Effects of High Pressure in a Rat Ex Vivo Glaucoma Model
Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
research Finasteride, a 5α-Reductase Inhibitor, Potentiates Antinociceptive Effects of Morphine, Prevents the Development of Morphine Tolerance and Attenuates Abstinence Behavior in the Rat
Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.
research Ranitidine And Finasteride Inhibit The Synthesis And Release Of Trimethylamine N-Oxide And Mitigate Its Cardiovascular And Renal Damage Through Modulating Gut Microbiota
Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.
research The 5α-Reductase Inhibitor Finasteride Exerts Neuroprotection Against Ischemic Brain Injury in Aged Male Rats
Finasteride helps protect brain in old male rats.
research Progesterone-Independent Neurosteroid Regulation of Alpha2-GABA-A Receptors in the Hippocampus Subfields
Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.
research Exploring the Neural Mechanisms of Finasteride: A Proteomic Analysis in the Nucleus Accumbens
Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
research Finasteride Inhibited Brain Dopaminergic System and Open-Field Behaviors in Adolescent Male Rats
Finasteride affects young male rats' brain function and behavior negatively.
research Exome-Wide Age-Of-Onset Analysis Reveals Exonic Variants In ERN1 And SPPL2C Associated With Alzheimer’s Disease
Researchers found two new genetic variants linked to Alzheimer's disease.
research The Anxiolytic-Like Effects of Estazolam on a PTSD Animal Model
Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.
research Molecular Basis of Androgen Action on Human Sexual Desire
Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
research Alcohol Exposure During Late Adolescence Increases Drinking in Adult Wistar Rats, an Effect That Is Not Reduced by Finasteride
Alcohol in teen years leads to more adult drinking, finasteride doesn't help.
research 25 Years of Estrogen Receptor Beta: A Personal Journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
research Pediatric Bipolar Disorder: Evidence-Based Psychopharmacological Treatments
Combining mood stabilizers with antipsychotics is more effective for treating children with bipolar disorder than using mood stabilizers alone.
research Repurposing Steroidogenesis Inhibitors for the Therapy of Neuropsychiatric Disorders: Promises and Caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
research Reduced Serum Brain-Derived Neurotrophic Factor in Patients with First Onset Vitiligo
People with first-time vitiligo have lower levels of a certain brain protein compared to healthy individuals.
research The Androgen Receptor Gene Polyglycine Repeat Polymorphism Is Associated With Memory Performance In Healthy Chinese Individuals
Certain gene variations are linked to better memory in healthy Chinese women.