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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Innovative methods are reducing animal testing and improving biomedical research.

Radiation significantly slows down wound healing in mice.

ILC1-like cells can cause alopecia areata by attacking hair follicles.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Forensic hair analysis for drugs is now more reliable and accurate.

LED therapy can safely and effectively regrow eyebrows in people with frontal fibrosing alopecia.

A method was found to accurately measure spironolactone and canrenone in blood samples using liquid chromatography-mass spectrometry.

QR 678 and QR678 Neo treatments are effective for hair loss in women with PCOS.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

High-dose androgen therapy can help manage certain types of androgen resistance.

Combining high-dose corticosteroids with methotrexate may be effective and safe for severe alopecia areata.

High-dose vitamin A was safe and well-tolerated in a lung cancer treatment study.

High-dose methotrexate can cause severe skin and nail issues.

High-dose vitamin A and E with zinc improved blood sugar control and insulin function in diabetics, but may cause hair loss.

Early high-dose steroid treatment helps prolong disease-free periods in severe alopecia areata.

High-dose corticosteroids and methotrexate had a modest effect on severe childhood alopecia, but side effects and relapse were concerns.

High-dose calcium pantothenate can reverse grey hair in some cases.

Higher doses of spironolactone may improve acne in PCOS patients, but side effects are a concern.

High-dose vitamin D3 does not improve symptoms or quality of life in COVID-19 patients after one year.

High doses of white turi flower extract increase sodium and potassium levels in rat kidneys.

Hepatitis B vaccination can trigger HSP, and vitamin D correction and tonsillectomy can effectively manage it.

High-dose corticosteroids can significantly regrow hair in severe alopecia areata.

High-dose finasteride effectively treats hair loss in postmenopausal women.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.