TLDR High-dose corticosteroids can significantly regrow hair in severe alopecia areata.
The study investigates the effectiveness of intravenous high-dose pulse corticosteroid therapy in treating alopecia areata universalis, a severe form of hair loss. The authors report that this treatment can lead to significant hair regrowth in patients, highlighting its potential as a viable therapeutic option. The findings suggest that high-dose corticosteroids may help modulate the immune response responsible for hair loss in alopecia areata universalis. The study emphasizes the need for further research to optimize treatment protocols and understand long-term outcomes.
44 citations,
April 2017 in “International Journal of Dermatology” No treatment is completely effective for alopecia totalis and alopecia universalis.
50 citations,
January 2016 in “Journal of the American Academy of Dermatology” Pulse steroid therapy for alopecia areata shows a 43% complete response rate but has a high relapse rate, especially in children.
1 citations,
August 2023 in “Acta dermato-venereologica” Corticosteroids are the most common treatment for alopecia areata, but many patients need better options.
6 citations,
November 2022 in “Journal of autoimmunity” JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
October 2022 in “Journal of Armed Forces Medical College, Bangladesh” Tofacitinib is effective and safe for treating alopecia areata.
39 citations,
April 2016 in “Case Reports in Dermatology” Tofacitinib temporarily regrew hair in a man with alopecia, but its effects didn't last.
5 citations,
June 2015 in “Veterinary dermatology” A dog with complete hair loss regrew most hair after treatment, with no relapse after stopping treatment.
39 citations,
April 2003 in “Australasian journal of dermatology” PUVA treatment led to significant hair regrowth in over half of the patients with alopecia areata totalis and universalis.
