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Finasteride treatment lowers urine androgen and prostaglandin levels, making them potential markers for effectiveness.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The Rotterdam Study aims to understand various diseases in older adults.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Fluoxetine was not effective in treating hair-pulling disorder in the short term.

Minoxidil effectively lowers blood pressure with few side effects.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.