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Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Trichoscopy is a quick, noninvasive method to diagnose hair and scalp disorders, often reducing the need for biopsies.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Some breast cancer chemotherapy can cause permanent hair loss.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

No cure for female pattern hair loss, but various effective treatments exist.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Tight hairstyles and chemical relaxers can cause hair loss known as traction alopecia.

Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

HIV can cause unusual and severe skin problems that are hard to treat.

Zinc supplements can resolve skin issues caused by zinc deficiency.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Newly made nicotinamide compounds could potentially treat cancer.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

The objective approach for creating search strategies is as effective as the traditional method and might be better and more efficient.