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Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Hair can indicate early signs of metabolic disorders, with issues like protein deficiency stopping hair growth.

Some skin diseases and anaemia are related, and treating the skin condition can often improve the anaemia.

Doctors often diagnose Cushing's syndrome late, which worsens symptoms; earlier detection is needed.

Type 2 diabetes does not change how metformin works in obese pregnant women, so dosage adjustments are not needed.

Children with autoimmune gastritis showed improved intestinal health over time and should be checked for other autoimmune conditions.

The document concludes that scalp disorders can be treated with hair washing, specific shampoos, medications, and sometimes surgery or hair transplants, but hereditary baldness is untreatable.

Citrullus colocynthis and Citrullus lanatus have potential health benefits but may also cause reproductive toxicity.

Platelet Rich Plasma (PRP) injections can effectively reduce hair loss and improve hair growth in both men and women suffering from androgenic alopecia.

Multiple plasma donations do not change donors' biochemical parameters.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Putting calcipotriol ointment on the skin once doesn't change calcium levels in the body right away.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

Taking calcium may help elderly with osteoporosis, birth control with levonorgestrel doesn't increase heart attack risk, Salmonella can cause arthritis, a national ethics committee is recommended, and sulfasalazine might help with a hair loss condition.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The document concludes that various clinical methods are used to assess ageing skin and the effectiveness of anti-ageing products.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.