Platelet Rich Plasma in Androgenic Alopecia in Male and Female Patients: A Myth, A Prospective Study

May 2018 in “ Journal of Evolution of medical and Dental Sciences ”

Jhansi Lakshmi S, Dhanya Sri, Rupa Ramani J, Shaik Asha, Naveen Kumar, Sameera Sameera, Amrutha Bindhu, Hanusha Hanusha

androgenic alopecia minoxidil finasteride Platelet Rich Plasma PRP dermal papillary cells apoptosis hair pull test Rogaine Propecia

TLDR Platelet Rich Plasma (PRP) injections can effectively reduce hair loss and improve hair growth in both men and women suffering from androgenic alopecia.

From July 2014 to June 2015, a study was conducted on 32 patients suffering from androgenic alopecia who were unresponsive to minoxidil and finasteride. These patients were treated with Platelet Rich Plasma (PRP) injections, which were found to promote the proliferation of dermal papillary cells and prevent their apoptosis, contributing to hair growth. The treatment involved injecting 2 to 3 cc of PRP into the scalp every 2 weeks for a total of 4 times. Significant reduction in hair loss was observed between the 1st and 4th injections, and significant improvement in hair growth was noted after the 6th injection in 22 patients. The hair pull test became negative in 13 of these cases, indicating a reduction in hair loss. The study concluded that PRP is a cost-effective and feasible treatment option for androgenic alopecia in both male and female patterns, despite the limitations of a small sample size and short follow-up period.

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Research cited in this study

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research Platelet-Rich Plasma Injection Is Effective and Safe for the Treatment of Alopecia

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research Effects of Epidermal Growth Factor, Fibroblast Growth Factor, Minoxidil, and Hydrocortisone on Growth Kinetics in Human Hair Bulb Papilla Cells and Root Sheath Fibroblasts Cultured In Vitro

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EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.

research Topical Minoxidil in Early Male Pattern Baldness

138 citations, August 1985 in “Journal of The American Academy of Dermatology”

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