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Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

Poliosis circumscripta is a patch of white hair caused by lack of melanin, linked to genetic and acquired conditions.

Early detection of specific skin lesions can help identify Birt-Hogg-Dube syndrome and prevent serious complications.

ACBP is crucial for healthy skin in mice.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

The treatment improved hair growth in people with male pattern baldness.

Increased scalp sweating in frontal fibrosing alopecia may be linked to local skin inflammation.

Deferasirox combined with sorafenib reduces liver cancer risk and lessens treatment side effects.

Birt–Hogg–Dubé Syndrome requires genetic testing for accurate diagnosis due to its similarities with tuberous sclerosis.

Athletic trainers are crucial in spotting and managing eating disorders in athletes.

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

Valproic acid can cause dark lines on nails.

The authors agree they didn't follow the original criteria strictly but found the Ottawa rule effective in all tested patients and suggest it might have wider use.

Skin tumor cells in patients with tuberous sclerosis have higher levels of a protein called cathepsin B.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

People with Birt-Hogg-Dubé syndrome often have lung problems and delayed diagnosis, and better recognition of CT scan signs could improve diagnosis and management.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Early intervention and tailored management can reduce skin side effects from cancer treatments.

Epidermal nevi are skin cell clusters linked to various syndromes.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

Treating H. pylori infection might help cure alopecia areata.

Royal jelly can protect the heart from damage caused by paclitaxel.