April 2021 in “Arab Journal of Nuclear Sciences and Applications/Arab Journal of Nuclear Sciences and Applications ” This study found that repeated use of a protein hair conditioner, followed by hot air and gamma irradiation, may lower serum collagen I and increase heat shock protein concentrations in rats, suggesting potential cumulative risks.
January 2026 in “American Journal of Translational Research” In this study, the combination of metoprolol and spironolactone in patients with coronary heart disease and heart failure significantly improved cardiac function and reduced inflammation and oxidative stress markers compared to spironolactone alone, with better clinical efficacy and fewer adverse effects.
69 citations
,
November 2010 in “Middle East Fertility Society Journal” This review discusses the multifactorial origins and pathophysiology of PCOS and highlights the effectiveness of lifestyle modifications as a first-line intervention, reporting no new research results.
75 citations
,
June 1999 in “Pediatric Clinics of North America” This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.
52 citations
,
August 2021 in “Microorganisms” This review observes higher ACE2 expression in myocardial and lung tissues of heart failure and COPD patients but finds no link between RAAS inhibitors and COVID-19 severity.
April 2023 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” This study compared the effects of direct heat perms and softening heat perms on hair, analyzing damage and morphological changes to understand their impact on hair fibers and provide foundational data for future research.
July 2026 in “Frontiers in Endocrinology” This study observed that beef cattle with certain prolactin receptor gene mutations, known as slick mutations, demonstrated improved post-weaning growth and temperature regulation in a hot, humid climate compared to other genotypes, suggesting genotype influences growth efficiency and heat tolerance.
30 citations
,
March 2001 in “Environmental Health Perspectives” This review explores the significant impacts of hormonal changes within normal physiological ranges and suggests examining low-dose effects from chemicals disrupting hormonal activity; it presents no new clinical results.
2 citations
,
April 2025 in “Cells” This study found that heat preconditioning of nanofat from mice did not improve tissue vascularization or integration in grafting, and actually reduced vascularization due to increased expression of anti-angiogenic factors, suggesting it is not beneficial for enhancing its vascularization properties.
10 citations
,
December 2018 in “Journal of animal physiology and animal nutrition” This study found that heat stress in rex rabbits decreased hair follicle density and suppressed related signaling pathways, potentially affecting hair follicle development.
3 citations
,
October 2022 in “Han'gug dongmul jawon gwahag hoeji/Han-guk dongmul jawon gwahak hoeji/Journal of animal science and technology” This study found that L-glutamine supplementation in Hanwoo steers under heat stress did not affect growth performance or muscle and adipose tissue gene expression but was associated with increased immune cells and reduced HSP90 expression.
12 citations
,
January 2007 in “Current problems in dermatology” This review discusses the impact of various exogenous agents on hair, such as cosmetics and radiation, but reports no new experimental results.
November 2023 in “Ensaios e Ciência C Biológicas Agrárias e da Saúde” In this study, researchers found that the concentrations of cetostearyl alcohol, shea butter, and coconut oil significantly affected the in vitro spreadability of heat protectants, suggesting that optimizing these components could improve product coverage and thermal protection on hair.
2 citations
,
January 2021 in “Cureus” This case report examines the long-term impact of extensive anabolic-androgenic steroid use on metabolic and cardiovascular health, highlighting adverse effects to guide primary care for this patient group.
418 citations
,
June 2003 in “Endocrine Reviews” This review discusses the relationship between polycystic ovary syndrome and cardiovascular risk, noting a possible adverse impact on risk profiles and subclinical atherosclerosis but no clear increase in premenopausal cardiovascular events; it presents no new clinical results.
34 citations
,
May 2017 in “Seminars in Reproductive Medicine” This review discusses the known morbidities of polycystic ovarian syndrome, highlighting its diverse impacts on women's health, but reports no new research findings.
September 2018 in “PubMed” This review discusses the aging-related changes in hair properties, their impact on styling, and potential interventions, without providing new clinical results.
1533 citations
,
October 2008 in “Endocrine reviews” This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.
56 citations
,
December 2011 in “Steroids” This review discusses the genetics and variable phenotypic expression of nonclassic congenital adrenal hyperplasia, and reports no new clinical results; the authors call for further research on long-term health impacts and treatment strategies.
2 citations
,
January 1970 in “Asian journal of pharmaceutical research and development” This review discusses the varying prevalence, symptoms, and potential genetic factors associated with Polycystic Ovary Syndrome in different populations, including its significant health impacts, and reports no new data on India's prevalence.
1 citations
,
December 2024 in “Journal of Education Health and Sport” In this review, anabolic steroid use was reported to increase risks such as cardiovascular issues, liver damage, endocrine disruptions, and musculoskeletal injuries, with psychological impacts also noted, underscoring the need for education and preventive strategies.
This review explores the risk factors, associated comorbidities, and psychological impacts of early-onset androgenetic alopecia, highlighting its complexity and potential implications for treatment response and overall health.
August 2008 in “Obstetrics & gynecology science” This review discusses the various features, diagnostic challenges, and associated immediate and long-term morbidities of polycystic ovary syndrome, highlighting its significant impact on quality of life and costs, but reports no new clinical results.
47 citations
,
May 2020 in “Cardiovascular Research” This review explores how sex differences influence the pathophysiology, incidence, and treatment outcomes of ischaemic heart disease, and emphasizes the need for more sex-specific research.
1 citations
,
January 2015 in “Zdravstvena zastita” This study highlights that workplace stress significantly contributes to various health issues, impacting worker performance and increasing absenteeism.
May 2026 in “International Journal of Drug Delivery Technology” This source describes how androgenic alopecia, or pattern hair loss, affects about 70% of men and is linked to factors like stress, hormonal imbalances, and lifestyle issues, which can also impact psychological well-being and potentially contribute to severe health conditions such as heart disease.
August 2020 in “Research Square (Research Square)” This study found that an age-adjusted Charlson comorbidity index of four or more strongly predicts mortality in South Korean COVID-19 patients, highlighting the impact of comorbidity burden and older age on disease severity.
8 citations
,
June 2019 in “Pharmaceutical research” This study found that using short durations of heat with chemical penetration enhancers improved isotretinoin delivery to human skin, especially via the hair follicles.
3 citations
,
January 2023 in “International Journal of Molecular Sciences” This review summarizes current knowledge on the role of heat shock proteins in the pathogenesis of PCOS and their potential implications in developing new treatment strategies, but it reports no new experimental results.
4 citations
,
February 2024 in “Biomedicine” The authors concluded that specific comorbidities and complications increase the risk of severe COVID-19 and impede patient recovery, making them critical factors to control in order to lessen the disease's adverse effects.