research Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells
Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.
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research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research Androgen Receptors And Their Biology
Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
research Proxalutamide Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial
Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.
research Androgens and Human Hair Growth
Androgens can cause hair growth in some areas and hair loss on the scalp.
research Androgen Receptor Copy Number Variation and Androgenetic Alopecia: A Case-Control Study
No clear link between androgen receptor variation and hair loss, but more research needed.
research Synthesis and Application of Clinically Approved Small-Molecule Drugs Targeting Androgen Receptor
Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research Proxalutamide Significantly Accelerates Viral Clearance and Reduces Time to Clinical Remission in Patients with Mild to Moderate COVID-19: Results from a Randomized, Double-Blinded, Placebo-Controlled Trial
Proxalutamide helps COVID-19 patients get rid of the virus faster and recover quicker.
research In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach
Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
research Insight into Recent Advances in Degrading Androgen Receptor for Castration-Resistant Prostate Cancer
New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.
research Early Onset and Novel Features in a Spinal and Bulbar Muscular Atrophy Patient with a 68 CAG Repeat
A patient with a larger than usual genetic mutation had a broader range of symptoms for a muscle disease.
research Differential Expression of CXCL12 in Human and Mouse Hair: Androgens Induce CXCL12 in Human Dermal Papilla and Dermal Sheath Cup
Targeting CXCL12 may help treat hair loss caused by androgens.
research Androgens and Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Androgens and Androgen Receptor Action in Skin and Hair Follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research Dexamethasone, a Synthetic Glucocorticoid, Induces the Activity of Androgen Receptor in Human Dermal Papilla Cells
Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
research Intrinsic Versus Extrinsic Aging: A Histopathological, Morphometric, and Immunohistochemical Study of Estrogen Receptor β and Androgen Receptor
The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.
research Maternal Androgen Excess Induces Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Mice Offspring
High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
research Hypogonadism as a Reversible Cause of Torsades de Pointes in Men
Low testosterone can cause a heart rhythm problem in men, but fixing it can prevent the issue.
research Cardiometabolic Risk Factors in Women with Non-Classic Congenital Adrenal Hyperplasia
Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.
research Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study
Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.
research The Evaluation and Treatment of Androgen Excess
High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.
research Is Dihydrotestosterone a Classic Hormone?
Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.
research Androgen Receptor in Human Health: A Potential Therapeutic Target
The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
research Structural Perspectives on the Androgen Receptor, the Elusive Shape-Shifter
The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.
research Sexual Hormones in Human Skin
Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
research Effects of Dihydrotestosterone on Rat Dermal Papilla Cells In Vitro
Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
research Role of Insulin Resistance and Diet in Acne
Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
research The Natural History of Androgenetic Alopecia
AGA affects many, progresses differently, and early treatment is crucial.
research Microarray Analysis of Androgenetic and Senescent Alopecia: Comparison of Gene Expression Shows Two Distinct Profiles
The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.