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Minoxidil lowers blood pressure more effectively but has more side effects, so try hydralazine first.

Malnourished Andean Indian children had abnormal hair roots compared to healthy children.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

A man's skin condition, pemphigus vulgaris, came back after he was treated with interleukin 2 for cancer.

Longer contact time increases minoxidil absorption, but doesn't affect metabolism.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.

Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

Finasteride cream helps hair growth with less side effects.

Low-dose finasteride reduces excessive hair growth in teenage girls safely and affordably.

Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

Minoxidil was first made for high blood pressure, but it was later found to help hair growth.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

New drugs and combination therapies are improving treatment for lower urinary tract symptoms.

Rice bran extract might help prevent hair loss.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.