3 citations,
January 2019 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
3 citations,
March 2016 in “Experimental Dermatology” A mutation in the hairless gene speeds up severe itchy skin in mice on a special diet.
3 citations,
April 2012 in “Fertility and Sterility” Finasteride may cause infertility in rats by affecting epididymis and sperm function.
3 citations,
March 2010 in “Dermatologica Sinica” A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.
3 citations,
June 1997 in “Veterinary Dermatology” Minoxidil treatment can stimulate hair growth in hairless puppies if applied early.
2 citations,
June 2000 in “Journal of The American Academy of Dermatology” Mutation in hairless gene may increase hair loss risk.
November 2005 in “Nature Reviews Molecular Cell Biology” The protein hairless is important for hair regrowth because it stops the protein wise from blocking the hair cycle.
August 2020 in “Pakistan Journal of Zoology” A new mutation in the Hairless gene causes hair loss in two Pakistani families.
June 1996 in “Journal of Dermatological Science” Vitamin D3 applied to mouse skin caused more wrinkles and sagging due to changes in the skin's outer layer.
4 citations,
January 1996 in “British journal of dermatology/British journal of dermatology, Supplement” Mexican hairless dogs can help test new skin treatments.
36 citations,
September 1999 in “Toxicologic pathology” Stronger corticosteroids cause more skin damage in hairless dogs, similar to effects in humans.
19 citations,
July 2009 in “Clinical and Experimental Dermatology” The study found that long-term sun exposure does not significantly affect follicular plugs on the scalp, and the scalp's appearance is unique compared to other body parts.
15 citations,
February 2015 in “Han-gug chugsan sigpum hag-hoeji/Korean journal for food science of animal resources” Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.
Mineral-rich spring water may promote hair growth better than Minoxidil in mice.
March 2012 in “Journal of The American Academy of Dermatology” Dermoscopy helps diagnose different hair loss conditions, and characteristics vary among ethnicities and individual cases.
74 citations,
November 2000 in “Archives of Dermatology” Salicylic acid can safely exfoliate and regenerate skin without causing inflammation.
50 citations,
December 2000 in “Journal of Pharmaceutical Sciences” Hair follicles significantly enhance electroosmotic transport during iontophoresis.
7 citations,
August 2017 in “PloS one” Key genes linked to hair growth and cancer were identified in hairless mice.
7 citations,
November 2011 in “Skin Research and Technology” The study found a specific pattern of uneven melanin distribution on balding scalps that could help understand skin diseases caused by light exposure.
2 citations,
December 2019 in “Archives of Craniofacial Surgery” Using a method of stretching skin multiple times can help cover large bald spots on the scalp, but it takes a long time and isn't good for kids.
1 citations,
November 2022 in “Journal of pharmaceutical negative results” Alopecia areata is an autoimmune condition causing patchy hair loss, with treatments focusing on immune system regulation and hair regrowth.
41 citations,
January 2014 in “Annals of Dermatology” Dermoscopic examination helps diagnose different types of hair loss conditions by showing specific patterns.
10 citations,
July 1980 in “British Journal of Dermatology” Topical putrescine and spermine increased DNA synthesis in hairless mouse skin.
2 citations,
March 1977 in “British Journal of Dermatology” Nandrolone phenylpropionate injections thickened the skin and enlarged oil glands in female hairless hamsters.
Heated radish extract may help lighten skin and reduce aging signs.
3 citations,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The unique coat of lykoi cats is likely caused by new variants in the Hairless gene.
October 2005 in “Nature reviews. Molecular cell biology (Print)” Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
December 2022 in “Curēus” Genetic testing confirmed a young girl has Atrichia with Papular Lesions due to mutations in the hairless gene.
Hairless mammals evolved quickly in both gene and non-gene areas related to skin and hair.
2 citations,
July 2013 in “Journal of Animal Physiology and Animal Nutrition” Shorthaired and hairless cat breeds excrete more felinine than longhaired breeds.