research How Much Health Insurance Is Enough? Revisiting the Concept of Underinsurance
The document concludes that there is no clear definition of adequate health insurance, and a consistent method to measure underinsurance is needed.
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research Endocrinological Evaluation and Hormonal Therapy for Women with Difficult Acne
Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.
research Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Anatomic Location of Primary Melanoma: Survival Differences and Sun Exposure
Where melanoma is on the body affects survival chances; melanomas on the back of the head are worse, while those on thighs and arms are less severe, and more sun exposure might improve survival.
research Non-Canonical Dimerization of the Androgen Receptor and Other Nuclear Receptors: Implications for Human Disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Therapeutic Applications and Pharmacoeconomics of Microneedle Technology
Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.
research Human Gene Correlation Analysis: A Tool for the Identification of Transcriptionally Co-Expressed Genes
The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.
research Clinical Risk Factors Associated with Intraoperative Floppy Iris Syndrome: A Prospective Study
Taking tamsulosin or finasteride and being older increase the risk of floppy iris during cataract surgery.
research Topical Gene Electrotransfer to the Epidermis of Hairless Guinea Pig by Non-Invasive Multielectrode Array
The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.
research Acquired Trichomegaly of the Eyelashes and Hypertrichosis Induced by Bimatoprost
Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.
research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Twenty-Five and Up Study: A New Wave of the Brisbane Longitudinal Twin Study
The 25Up study collected extensive data on mental disorders and related factors in Australian twins and siblings to investigate the genetics of psychiatric illnesses.
research Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis
Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
research Structure Optimization of Tetrahydropyridoindole-Based Aldose Reductase Inhibitors Improved Their Efficacy and Selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Peri-Xanthenoxanthene (PXX): A Versatile Organic Photocatalyst in Organic Synthesis
PXX is an effective and affordable photocatalyst for creating new chemical bonds in organic synthesis.
research Dual Inhibitors of Urease and Carbonic Anhydrase-II from Iris Species
Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.
research Effects of Oral Contraceptives on the Quality of Life of Women with Polycystic Ovary Syndrome: A Crossover Randomized Controlled Trial
Birth control pills containing cyproterone acetate improve the quality of life more for women with polycystic ovary syndrome after 6 months of use.
research Evolution of Ritlecitinib Population Pharmacokinetic Models During Clinical Drug Development
Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.
research Basic Concepts, Current Evidence, And Future Potential For Gene Therapy In Managing Cutaneous Wounds
Gene therapy shows promise for improving wound healing, but more research is needed for human use.
research Serum Preptin and Amylin Levels with Respect to Body Mass Index in Polycystic Ovary Syndrome Patients
Women with PCOS have lower amylin levels, which are not related to their body weight.
research Somatization in Dermatology Patients: Sociocultural Perspectives
Skin symptoms without a medical cause often reflect psychological stress and are influenced by culture, requiring a team approach for treatment.
research A Tale of Two Haplotypes: The EDA2R/AR Intergenic Region Is the Most Divergent Genomic Segment Between Africans and East Asians in the Human Genome
The most different genetic segment between Africans and East Asians is the EDA2R/AR region, with two main types influenced by population changes and natural selection, and linked to baldness.
research Evaluation of Bioequivalence of Five 0.1 mg Dutasteride Capsules Compared to One 0.5 mg Dutasteride Capsule: A Randomized Study in Healthy Male Volunteers
Taking five small dutasteride capsules is the same as taking one larger capsule.
research Biotransformation of Finasteride by Ocimum Sanctum L., and Tyrosinase Inhibitory Activity of Transformed Metabolites: Experimental and Computational Insights
Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.
research MiR-29 Is an Important Driver of Aging-Related Phenotypes
miR-29 is a key factor that accelerates aging.
research Amendments to Organizational Theorizing
Karl E. Weick recommended focusing on everyday events and smaller organizations to improve organizational theory.
research MendelVar: Gene Prioritization at GWAS Loci Using Phenotypic Enrichment of Mendelian Disease Genes
MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.
research TCM Medicine and Food Homology in the Management of Post-COVID Disorders
Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.
research Illness and Femininity in Hilary Mantel’s Giving Up the Ghost
The document concludes that Hilary Mantel's memoir shows how childhood experiences affect adult health, criticizing modern medicine for ignoring the mental aspects of physical illness.
research The Impact of Medical Terminology in Self-Triage Decision-Making
Using complex medical terms can make people want to seek medical help faster.