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Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Sardinians were historically short due to a mix of genetics and factors like disease and poor nutrition, but recent height increases suggest better living conditions had a bigger impact.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Fibroblast state switching is crucial for skin healing and development.

Heavily hunted wolves have higher stress and reproductive hormone levels.

Hesperidin from orange peels is a promising natural ingredient for skincare due to its multiple beneficial properties.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Hair follicles create different cell layers and proteins, controlled by various molecules.

TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

Hair growth is cyclic and influenced mainly by local factors.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.

Fat-related cells are important for initiating hair growth.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Hair color is determined by melanin produced and transferred in hair follicles.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Most adult chronic hair pullers are women who started in their early teens, often have other mental health issues, and may pull hair due to underlying psychiatric conditions.

Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.

Hair follicle size and distribution vary significantly across different body sites.

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.