research Maternal Western Diet Causes Inflammatory Milk and TLR2/4-Dependent Neonatal Toxicity
A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
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360-390 / 1000+ results research Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Hairless mammals evolved quickly in both gene and non-gene areas related to skin and hair.
research The Genetics Of Alopecia Areata: New Approaches, New Findings, New Treatments
New genetic discoveries may lead to better treatments for alopecia areata.
research Genetic Control of Cytokines
Genes affect cytokine production, which can influence chronic diseases, and certain interventions may help prevent related molecular damage.
research Antiandrogenic Activity of Riboflavin 5′-Phosphate (FMN) in 22Rv1 and LNCaP Human Prostate Cancer Cell Lines
Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
research Transcriptome Analysis to Identify the Downstream Genes of Androgen Receptor in Dermal Papilla Cells
The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.
research Alopecia Areata Profiling Shows lncRNAs Regulate the Suppressed Expression of Keratin
Certain RNAs may help diagnose alopecia areata by affecting keratin genes.
research The TFIID Subunit TAF4 Regulates Keratinocyte Proliferation and Has Cell-Autonomous and Non-Cell-Autonomous Tumor Suppressor Activity in Mouse Epidermis
TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
research Integrated miRNA and mRNA Analysis Provides New Insight into Mechanism of Dermal Papilla in Androgenetic Alopecia
Increased cell death and reduced cell growth in hair follicles contribute to baldness.
research In The Quest To Stymie Time, Will Laboratory Data Stand Up In Man?
Genetic manipulations that extend lifespan in mice may not work as effectively in humans.
research A Polygenic Mouse Model of Psoriasiform Skin Disease in CD18-Deficient Mice
CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.
research Activation of Nrf2 in Keratinocytes Causes Chloracne-Like Skin Disease in Mice
Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
research Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity
Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
research Autophagy: Guardian of Skin Barrier
Autophagy helps keep skin healthy and may improve treatments for skin diseases.
research Elucidating the Anti-Aging Mechanism of Si Jun Zi Tang by Integrating Network Pharmacology and Experimental Validation In Vivo
Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.
research Alternative Splicing Factor Esrp1 Controls Homeostasis of Skin by Regulating Barrier Formation and Function
Esrp1 is important for skin health by helping form and maintain the skin barrier.
research Ligand-Independent Actions of Vitamin D Receptor
The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.
research Effects of Crataegi Fructus Water Extract on Hair Growth and Gene Expression in Dermal Papilla Cells
Crataegi Fructus water extract helps hair grow better and thicker.
research Alopecia Areata: Animal Models
Alopecia areata is influenced by genetics and immune system factors, and better understanding could improve treatments.
research Therapeutic Application of Microsponges-Based Drug Delivery Systems
Microsponges delivery system is a safe, versatile method for controlled drug release in various treatments.
research Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies?
Studying rare genetic disorders can help us understand and treat common diseases better.
research A Review of the Etiologies, Clinical Characteristics, and Treatment of Canities
Gray hair is caused by reduced melanin production or transfer issues, linked to aging and possibly health conditions, with treatments focusing on color camouflage.
research Frontal Fibrosing Alopecia: Just Lichen Planopilaris?
Frontal Fibrosing Alopecia may be a complex condition linked to hormonal changes in women, not just a form of Lichen Planopilaris.
research Recent Advances in the Molecular Mechanisms Causing Primary Generalized Glucocorticoid Resistance
Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
research Dermatological Diseases from a Genetic Perspective
New gene discoveries have improved diagnosis and treatment for skin and hair disorders, but more research is needed to fully understand them.
research Alopecia Areata: Genetic and Immunological Insights
Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.
research Genetic Basis of Alopecia Areata
More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.
research Alterations in Transcriptome and Antioxidant Activity of Naturally Aged Mice Exposed to Selenium-Rich Rice
Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.
research Mapping of a Novel Locus for Keratosis Follicularis Squamosa on Chromosome 7p14.3–7p12.1
A new gene location for Keratosis follicularis squamosa was found on chromosome 7p14.3-7p12.1.
research Application of Multi-Omics Techniques to Androgenetic Alopecia: Current Status and Perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.