14 citations,
July 2021 in “Biomolecules” Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.
14 citations,
April 2021 in “International journal of molecular sciences” Mesenchymal stem cells may help treat hair loss by improving hair cell growth and reducing inflammation.
14 citations,
May 2017 in “InTech eBooks” Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.
7 citations,
September 2017 in “Scientific Reports” Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
3 citations,
March 2023 in “Biology” Genes affecting wool fiber thickness in Angora rabbits were identified, which could help breed finer wool.
1 citations,
January 2017 in “Elsevier eBooks” The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
N793 may improve hair density in people with mild hair thinning.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
326 citations,
February 2009 in “The American journal of pathology” Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
49 citations,
November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
42 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
27 citations,
August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found new genes involved in hair growth, which could help develop new hair treatments.
6 citations,
March 2019 in “Dermatologic surgery” Chilled ATPv-supplemented saline best preserves hair grafts' key genes.
2 citations,
August 2016 in “Lasers in Surgery and Medicine” Photodynamic therapy can remove nonpigmented hair in mice and might work for humans.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
121 citations,
March 1989 in “Journal of Investigative Dermatology” Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.
K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.
6 citations,
August 2007 in “Journal of Surgical Research” Mice genetically modified to produce more Del1 protein had faster hair regrowth.
105 citations,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
33 citations,
August 2015 in “F1000Research” New model shows muscle affects hair loss differently in men and women.
3 citations,
July 2015 in “European Journal of Dermatology” AGEs may cause hair loss by increasing inflammation in hair follicles.
46 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
31 citations,
April 1999 in “Dermatologic Clinics” Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
28 citations,
October 2011 in “International Journal of Molecular Medicine” Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
26 citations,
October 2007 in “Experimental Dermatology” L-Carnitine-L-tartrate may help hair grow and prevent hair loss.
8 citations,
January 2013 in “The scientific world journal/TheScientificWorldjournal” Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.
210 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.
271 citations,
March 1999 in “Developmental biology” The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
88 citations,
May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.