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Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.

Aging men face unique health issues like erectile dysfunction, prostate problems, and baldness.

CD4+ skin cells may be precursors to basal cell carcinoma.

Higher sebum levels are linked to more severe male baldness.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Different connective tissue disorders have unique symptoms and treatments, with varying outcomes and often require ongoing care from a specialist.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.

Loss of keratin K2 causes skin problems and inflammation.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

The normal human prostate does not significantly affect blood DHT levels.

New drugs for heart disease may be developed from molecules secreted by stem cells.

Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.