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    Did you mean Hair Cycle Clock?
    Glossary Hair Cycle Clock

    internal mechanism regulating hair growth, rest, and shedding phases

    The Hair Cycle Clock refers to the internal biological mechanism that regulates the phases of hair growth, rest, and shedding. This cycle includes the anagen (growth), catagen (transitional), and telogen (resting) phases, ensuring that hair follicles undergo a synchronized process of renewal and shedding. Understanding this clock is crucial for diagnosing and treating hair disorders like alopecia.

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    1. Lgr5 marks cycling, yet long-lived, hair follicle stem cells Nature Genetics · 2008 · 835 citations
    2. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011 · 499 citations
    3. The hair cycle Journal of Cell Science · 2006 · 375 citations
    4. Molecular Control of Epithelial–Mesenchymal Interactions During Hair Follicle Cycling 2003 · 277 citations
    5. Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling Journal of Biological Chemistry · 2003 · 215 citations
    6. A Guide to Studying Human Hair Follicle Cycling In Vivo Journal of Investigative Dermatology · 2015 · 212 citations
    7. Dermal papilla cell number specifies hair size, shape and cycling and its reduction causes follicular decline Development · 2013 · 211 citations
    8. Keratin 17 modulates hair follicle cycling in a TN<i>Fα</i>-dependent fashion Genes & Development · 2006 · 169 citations
    9. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012 · 158 citations
    10. Molecular biology of hair morphogenesis: Development and cycling Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution · 2003 · 155 citations
    11. Hair cycle and hair pigmentation: dynamic interactions and changes associated with aging Micron · 2003 · 152 citations
    12. Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle ˜The œFASEB journal · 2010 · 149 citations
    13. The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling ˜The œAmerican journal of pathology · 2002 · 146 citations
    14. Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles Differentiation · 1994 · 130 citations
    15. Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents Journal of Investigative Dermatology · 2007 · 127 citations
    16. Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling Proceedings of the National Academy of Sciences of the United States of America · 2013 · 116 citations
    17. Hair-Cycle-Associated Remodeling of the Peptidergic Innervation of Murine Skin, and Hair Growth Modulation by Neuropeptides Journal of Investigative Dermatology · 2001 · 112 citations
    18. THE HAIR CYCLE OF THE MOUSE AND ITS IMPORTANCE IN THE STUDY OF SEQUENCES OF EXPERIMENTAL CARCINOGENESIS Annals of the New York Academy of Sciences · 1951 · 111 citations
    19. A simple immunofluorescence technique for simultaneous visualization of mast cells and nerve fibers reveals selectivity and hair cycle - dependent changes in mast cell - nerve fiber contacts in murine skin Archives of Dermatological Research · 1997 · 109 citations
    20. Principles of Hair Cycle Control The Journal of Dermatology · 1998 · 109 citations
    21. The hair cycle Journal of Cell Science · 2006 · 103 citations
    22. Genetic Ablation of the <i>CDP/Cux</i> Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility Molecular and cellular biology · 2002 · 97 citations
    23. Hair follicle expression of 1,25-dihydroxyvitamin D3 receptors during the murine hair cycle British Journal of Dermatology · 2006 · 95 citations
    24. Cyclic hair-loss and regrowth in transgenic mice overexpressing an intermediate filament gene. The EMBO Journal · 1990 · 93 citations
    25. A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock Journal of Investigative Dermatology · 2013 · 92 citations
    26. Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes Proceedings of the National Academy of Sciences of the United States of America · 2006 · 92 citations
    27. Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor (ER)-α Is Checked by ERβ Signaling Endocrinology · 2005 · 92 citations
    28. Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen American Journal of Pathology · 2003 · 91 citations
    29. Hair cycle-specific expression of versican in human hair follicles Journal of Dermatological Science · 2005 · 88 citations
    30. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables Experimental dermatology · 2001 · 86 citations