April 2017 in “Journal of Investigative Dermatology” Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.
April 2017 in “Journal of Investigative Dermatology” April 2018 in “Journal of Investigative Dermatology” Hair follicle stem cells can change their role to ensure proper hair development.
April 2018 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
Human scalp hair follicles have PGE2 and its receptors, which might affect hair growth.
256 citations,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Growing human skin cells in a 3D environment can stimulate new hair growth.
66 citations,
August 2001 in “Experimental Dermatology” Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.
38 citations,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
29 citations,
August 2017 in “Skin appendage disorders” IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.
24 citations,
February 2006 in “Chinese Medical Journal” Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.
17 citations,
December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
15 citations,
July 2016 in “Biochemical Journal” Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
14 citations,
July 2015 in “Journal of Cosmetic Dermatology” Sebaceous glands in male pattern hair loss patients have more lobules and might cause early hair growth phase shifts.
11 citations,
October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
11 citations,
June 2012 in “Acta histochemica” Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.
9 citations,
January 2008 in “Acta histochemica et cytochemica” COX-2 levels change during the hair cycle and affect skin and hair growth.
8 citations,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
4 citations,
September 2016 in “Molecular Medicine Reports” Specific genes influence hair and cashmere growth in Laiwu black goats.
1 citations,
January 2019 in “Elsevier eBooks” Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
170 citations,
July 2012 in “Journal of Investigative Dermatology” Wnt ligands are crucial for hair growth and repair.
102 citations,
August 2008 in “Genes & Development” Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
59 citations,
March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
51 citations,
January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
44 citations,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
43 citations,
July 2014 in “Experimental Dermatology” Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
40 citations,
March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
35 citations,
July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
32 citations,
December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” 17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.
31 citations,
April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
29 citations,
December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.