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Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

Epigenetic mechanisms control skin development by regulating gene expression.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Dermal EZH2 controls skin cell development and hair growth in mice.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Dermal EZH2 controls skin cell growth and differentiation in mice.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.