research Protein Disulfide Isomerase-Mediated Grafting of Cysteine-Containing Peptides onto Over-Bleached Hair
PDI helps restore over-bleached hair's strength and structure by attaching special peptides.
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research Optimization of Minoxidil Microemulsions Using Fractional Factorial Design Approach
The study found a way to improve a skin-applied minoxidil formula using a specific design method.
research Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
research Effect of Decellularized Extracellular Matrix Bioscaffolds Derived from Fibroblasts on Skin Wound Healing and Remodeling
A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.
research The Physicochemical, Biopharmaceutical, and In Vitro Efficacy Properties of Freeze-Dried Dexamethasone-Loaded Lipomers
Freeze-dried dexamethasone nanoparticles in a hydrogel are stable and effective for treating alopecia areata.
research Combination and Rotational Therapy in Androgenetic Alopecia
Using different hair loss treatments at various times can improve results and reduce side effects for people with chronic hair loss.
research A Comparative Study of Skin Transcriptomes and Histological Observations for Black and White Hair Colors of Giant Panda
The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.
research The Repairing of Full-Thickness Skin Deficiency and Its Biological Mechanism Using Decellularized Human Amniotic Membrane as the Wound Dressing
Human amniotic membrane helps heal skin wounds faster and with less scarring.
research Expression and Function of Nuclear Receptor Co-Activator 4: Evidence of a Potential Role Independent of Co-Activator Activity
NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
Vitexin Compound 1 may help reduce skin aging caused by UVA light.
research Modulation of the 6-Position of Benzopyran Derivatives and Inhibitory Effects on the Insulin Releasing Process
Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
research Efficacy and Safety of a New 10% Topical Minoxidil Versus 5% Topical Minoxidil and Placebo in the Treatment of Male Androgenetic Alopecia: A Trichoscopic Evaluation
10% minoxidil solution better promotes hair growth and reduces hair loss without significant side effects.
research Teratogenic Effect of Isotretinoin in Both Fertile Females and Males: A Review
Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.
research Thrombin Activatable Fibrinolysis Inhibitor and Other Hemostatic Parameters in Patients with Polycystic Ovary Syndrome
Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.
research Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells
Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
research The Structural and Functional Aspects of Hair Cell Regeneration in the Chick as a Result of Exposure to Intense Sound
Chickens exposed to loud noise can quickly regain hearing mostly due to repair of the tectorial membrane, not just hair cell regeneration.
research Hair Growth Promoting Effect of Essence Manufactured with Products Fermented by Lactobacillus Rhamnosus and Backryeoncho (Opuntia Ficus-Indica Var. Sarboten) Fruits in Mice
The essence made from fermented products increased hair growth in mice better than minoxidil.
research Expression and Tissue Distribution Analysis of Vimentin and Transthyretin Proteins Associated With Coat Colors in Sheep (Ovis Aries)
Vimentin and transthyretin proteins are linked to black coat color in sheep.
research In Vitro and In Vivo Structure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring
Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
research The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog Silurana Tropicalis
Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
research Blockade of S100A3 Activity Inhibits Murine Hair Growth
Stopping S100A3 activity slows down hair growth in mice.
research Androgen Receptors And Their Biology
Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
research Androgenic and Anti-Androgenic Effects of Progesterone Derivatives with Different Halogens as Substituents at the C-6 Position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Tofacitinib Loaded Squalenyl Nanoparticles for Targeted Follicular Delivery in Inflammatory Skin Diseases
Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.
![Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase](/images/research/d91300a7-4d66-4d2c-90ac-293b0dbc5ff5/small/21048.jpg)
research Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase
Compound 15a was effective in inhibiting 5α-reductase.
research Hair Strengthening Evaluation of Anisotropic Osmolyte Solutions (Inositol + Arginine): Cross-Talk Between Dermal Papilla Fibroblast and Keratinocytes of the Outer Root Sheath Using a Micro Hair Follicle 3D Model
Inositol and arginine solutions improve hair follicle health and turnover.
research Cyclooxygenases in the Skin: Pharmacological and Toxicological Implications
Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis
GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
research 5α-Reductase Inhibitors: The Finasteride Story
Finasteride safely treats enlarged prostate and male-pattern baldness.