April 2026 in “JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA” In this study, the researchers successfully developed a Spanlastic gel containing EGCG for transdermal application, significantly increasing EGCG skin permeability with optimal entrapment efficiency, zeta potential, and vesicle size.
3 citations
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June 2009 in “The journal of alternative and complementary medicine/Journal of alternative and complementary medicine” This letter discusses the potential of green tea extract as a treatment for hirsutism but reports no clinical outcomes.
8 citations
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April 2019 in “International journal of scientific research in biological science” This review discusses the natural habitat, taxonomy, phytochemical components, pharmacological activities, and potential medical applications of Tridax procumbens but reports no new experimental findings.
January 2015 in “Zurich Open Repository and Archive (University of Zurich)” This study found no significant difference in anagen rate improvement between the CYP-based dietary supplement and placebo in women over 60 with telogen effluvium, possibly due to variable patient inclusion related to hair growth seasonality.
March 2026 in “Inflammopharmacology” This study found that ursolic acid at 50 mg/kg improved biochemical, hormonal, and ovarian histopathological markers in a rat model of PCOS, suggesting its potential as a therapeutic option.
March 2026 in “Physical Education Health and Social Sciences” In this randomized controlled trial, combining cinnamon and inositol led to significant improvements in metabolic and hormonal parameters, such as reduced LH, testosterone, fasting glucose, and ovarian ultrasound scores, in overweight women with PCOS, indicating superior benefits over either supplement alone.
7 citations
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August 2007 in “Journal of Biotechnology”
20 citations
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February 2009 in “Chemistry & Biodiversity” This study found that Ganoderma lucidum extracts showed weak 5alpha-reductase inhibition but significantly inhibited prostate cell proliferation and testosterone-driven prostate growth in rats, suggesting potential as an ingredient for treating androgen-induced diseases.
January 2022 in “Journal of pharmacognosy and phytochemistry” This study found that a polyherbal gel made from guava leaves, amla, and aloe is effective against candidiasis on the skin, with additional benefits of nourishing hair and preventing premature graying.
August 2025 in “Frontiers in Pharmacology” This study identified three Ayurvedic compounds that may serve as potential treatments against the macrolide-resistant enzyme murE of *Tropheryma whipplei*, addressing challenges in treating Whipple disease.
4 citations
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January 2016 in “Journal of analytical & bioanalytical techniques” This study evaluated a hair growth gel with Hibiscus rosa sinensis, Eclipta alba, and Solanum nigrum extracts, demonstrating consistent homogeneity, 5 α-reductase inhibitory activity, and no skin irritation.
February 2024 in “Current Drug Delivery” In this study, researchers developed an emulgel formulation containing minoxidil for hair growth, using chitosan and fucoidan as gelling agents, achieving controlled drug release with 99.7% released by the 12th hour.
4 citations
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November 2023 in “Biological and Pharmaceutical Bulletin” This study found that the BP-3 extract from Boesenbergia rotunda, rich in panduratin A, demonstrated strong anti-adipogenesis and lipolysis effects on preadipocyte cells at non-toxic concentrations, and when formulated into a serum reduced thigh circumference and improved skin firmness in a human trial.
November 2024 in “Apple Academic Press eBooks” In this chapter, the authors emphasize the significant therapeutic roles attributed to Allium tuberosum due to its rich phytochemicals, detailing potential benefits against various conditions like diabetes, cancer, and liver dysfunction, as well as its applications in anticoagulation, muscle cell proliferation, and sensory perception mediation.
7 citations
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August 2006 in “Maturitas” This study found that black cohosh extract BNO 1055 reduced testosterone-induced prostate and seminal vesicle growth in rats, suggesting it may contain potent 5α-reductase inhibitors useful for prostate cancer prevention.
3 citations
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May 2021 in “PloS one” This study found that Jordanian males use oral contraceptive pills, particularly for bodybuilding, based on recommendations from gym coaches, highlighting unexpected uses of these medications.
September 2025 in “International Journal of Molecular Sciences” This review examined the potential effects of Kampo medicine Hangeshashinto on oral mucositis, highlighting that several natural products in its composition may inhibit intracellular AGEs, reduce inflammation from extracellular AGEs, and suppress cytotoxicity in stomatitis.
9 citations
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May 2021 in “Frontiers in aging neuroscience” This study found that long-term use of triterpenoids from Ganoderma lucidum may improve brain function and alleviate aging-related issues in normal and Alzheimer's mouse models.
1 citations
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March 2021 in “Journal of Experimental Biology and Agricultural Sciences” This study observed that consuming flaxseeds significantly reduced serum free testosterone and improved insulin levels among young women with PCOS, suggesting a promising alternative to conventional treatments.
April 2011 in “Journal of Medicinal Plants Research” This study found that Ocimum basilicum L. showed the highest 5α-reductase inhibitory activity among ten Thai plants, despite no correlation between enzyme inhibition and total phenolic content.
May 2026 in “VT International Press Journal of Multidisciplinary Research and Review” This study developed a herbal hair oil using garlic leaves, coconut oil, castor oil, hibiscus flower powder, and amla extract, finding it enhances scalp nutrition, reduces hair loss, and maintains favorable aesthetic attributes with appropriate stability and consistency for hair application.
November 2025 in “ACS Omega” This study found that compounds from *Tectona grandis* leaves showed moderate inhibition of steroid 5α-reductase, a factor in androgenetic alopecia, and exhibited anti-inflammatory properties by inhibiting nitric oxide and pro-inflammatory cytokines IL-1β and IL-6 in vitro, suggesting potential dual-action benefits for AGA management.
12 citations
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January 2019 in “Journal of Endocrinology” In this study, baicalin from Scutellaria baicalensis decreased androgen levels in both cells and PCOS model rats by inhibiting key gene expression, suggesting it may be a potential treatment for hyperandrogenism in PCOS.
July 2025 in “SKIN The Journal of Cutaneous Medicine” In this pilot study, preliminary data suggest that Xtressé™, a gummy-based supplement, may increase hair count and hair mass, particularly in women experiencing female pattern hair loss or early-stage scarring alopecia, with less pronounced effects observed in advanced scarring conditions.
51 citations
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November 1988 in “The Journal of Clinical Endocrinology & Metabolism” This study found that serum 3 alpha-Adiol-G levels in men are significantly associated with chest hair density and acne, indicating its role in reflecting androgen activity in peripheral tissues.
119 citations
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June 2021 in “Heliyon” This review examines the phytochemical constituents and pharmacological effects of licorice, discussing its potential health benefits and side effects without reporting new clinical results.
February 2026 in “Scientific Reports” This study predicted that key components of Platycladi Cacumen, such as quercetin and apigenin, may have stable binding interactions with targets involved in androgenetic alopecia.
7 citations
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April 1992 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” The authors concluded that plasma levels of 3α-diolG, ADTG, and DHTG in women with hyperandrogenic disorders primarily reflect adrenal androgen contributions rather than peripheral action, suggesting a potential index for treatment effectiveness.
June 2022 in “International Journal of Advanced Research in Science, Communication and Technology” This article discusses the composition and benefits of multivitamin gummies, emphasizing their palatability and potential health effects, but reports no new clinical findings.
8 citations
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January 2014 in “BioMed Research International” This study reported that among three plant extracts tested for hair growth on nude mice, Eclipta alba significantly increased hair density and length, unlike Asiasari radix and Panax ginseng.