Efficacy of Flaxseed Crackers in Ameliorating Clinical and Biochemical Hyperandrogenism in Young Adult South Indian Women Diagnosed with PCOS

    March 2021 in “ Journal of Experimental Biology and Agricultural Sciences ”
    Jeyamani Divya Christodoss, Priya D John, Vasantha Esther Rani
    TLDR Flaxseed crackers can help reduce symptoms of PCOS in young women.
    A study conducted among young South Indian women aged 20-25 with PCOS found that consuming flaxseed crackers significantly reduced serum free testosterone levels and improved clinical symptoms of hyperandrogenism, such as hirsutism. The randomized single-blind placebo-controlled trial showed that the flax group had lower free testosterone (1.02 ± 0.428 ng/dl) compared to the placebo group (1.64 ± 0.504 ng/dl). Although the increase in Sex hormone Binding Globulin (SHBG) levels was not statistically significant, it was higher in the flax group (15.22 ± 14.593 nmol/L) than in the placebo group (9.64 ± 5.124 nmol/L). Additionally, serum insulin levels were reduced in the flax group (15.67 ± 6.928 µU/mL) compared to the control group (19.09 ± 8.526 µU/mL). These effects were attributed to the phytoestrogen (SDG) in flaxseeds, suggesting they could be a promising alternative to conventional PCOS treatments.
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