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The document does not confirm if radical prostatectomy is the best treatment for locally advanced prostate cancer.

Serum triglyceride levels are not linked to prostate cancer risk.

Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.

The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Some people with primary cicatricial alopecia also have inflammatory bowel disease, suggesting a possible connection.

Dopaminergic therapy in Parkinson's disease patients is linked to increased hair loss.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

New compounds with carborane showed anti-androgen effects similar to flutamide.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Losartan can cause temporary loss of taste.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

New cell-based therapies may improve hair loss treatments in the future.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

Hedgehog pathway inhibitors used for skin cancer can cause significant hair loss, which may improve after stopping the medication.

Higher DHT in male baldness may protect against prostate cancer.

Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.