research Hormesis And Medicine: Biphasic Dose-Response Relationship
Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
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research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Chronic Inflammatory Diseases Stimulated by Current Lifestyle: How Diet, Stress Levels, and Medication Prevent Our Body from Recovering
Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.
research Phenotype and Metabolic Profile of South Asian Women with Polycystic Ovary Syndrome: Results from a Specialist Endocrine Clinic
South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.
research Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins
Skin-derived precursors in hair follicles come from different origins but function similarly.
research Laminin-511 Is an Epithelial Message Promoting Dermal Papilla Development and Function During Early Hair Morphogenesis
Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
research Androgenetic Alopecia: An Update
Minoxidil and finasteride effectively treat hair loss.
research Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases
Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.
research Alpha-Hydroxy Acid-Based Cosmetic Procedures
Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.
research Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables
Mutant mice help researchers understand hair growth and related genetic factors.
research Inhibition of SARS-CoV-2 Entry Through the ACE2/TMPRSS2 Pathway: A Promising Approach for Uncovering Early COVID-19 Drug Therapies
Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
research Clinical and Biological Impact of the Exposome on the Skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
research Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Hair Follicles’ Transit-Amplifying Cells Govern Concurrent Dermal Adipocyte Production Through Sonic Hedgehog
Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
research Management of Hair Loss
Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.
research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion
The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research A New Catalyst for Organic Synthesis: Mercuric Triflate
Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.
research Age-Induced Hair Greying: The Multiple Effects of Oxidative Stress
Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia
Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
research The Modulatable Stem Cell Niche: Tissue Interactions During Hair and Feather Follicle Regeneration
The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
research Progress on the Road to Better Medical Care for Transgender Patients
The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.
research Finasteride in the Treatment of Androgenetic Alopecia
Finasteride effectively treats male pattern baldness, improving hair growth and density.
research Fadrozole And Finasteride Exposures Modulate Sex Steroid- And Thyroid Hormone-Related Gene Expression In Silurana (Xenopus) Tropicalis Early Larval Development
Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
research Apoptosis and Cutaneous Biology
Apoptosis is crucial for healthy skin and treating skin diseases.
research Use of High-Dose Cyproterone Acetate and Risk of Intracranial Meningioma in Women: Cohort Study
High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.
research The Genetics of Hair Shaft Disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness
Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.
research Acne
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.