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This review provides a comprehensive synthesis of skin aging research, highlighting the interplay of genetic and environmental factors, cellular mechanisms, and advances in diagnostic and therapeutic strategies, while also addressing current debates and future directions in the anti-aging field.

In this study, the authors reviewed various herbal ingredients used in hair care products and found that components like aloe vera, hibiscus, amla, and fenugreek have traditional and scientifically validated benefits for addressing hair issues such as hair loss, dandruff, and damage.

This study found that volatile compounds from Bacillus subtilis strain WM13-24 improved root development in Arabidopsis by influencing auxin signaling.

This chapter provides an overview of phytochemicals with properties to combat alopecia and discusses the potential of flavonoids, found in several herbs, as a safer alternative to synthetic hair loss treatments due to their long-term skin compatibility.

This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.

This narrative review concludes that long-term randomized controlled trials are needed to establish clear guidelines for testosterone therapy in women, given the lack of FDA-approved formulations and the variable quality of current treatments.

This study developed and tested a shampoo with semi-permanent dyes designed to gradually cover gray hair, reporting maintained stability and effective gray–black coloration on high-canities hair tresses through eight wash cycles.

This study examined the factors contributing to gray hair, such as genetics and lifestyle, and found that while graying correlates with some health conditions, it is primarily a physiological process rather than a pathological one.

This study concluded that mixtures of weak endocrine disruptors, such as parabens and azole fungicides, can produce combination effects that should be considered in regulatory risk assessments to avoid underestimating potential risks.

This study reported that Soulflower Rosemary Redensyl Hair Growth Serum (Tetragain™) significantly improved hair growth, increased hair thickness, reduced hair fall, and decreased graying over 120 days, with participants rating the treatment as effective and experiencing no adverse effects.

This review discusses the harmful effects of coloring shampoos containing trihydroxybenzene on the scalp-skin barrier and emphasizes the need for safer ingredient selection to prevent side effects.

This study found that a non-ionic ethosomal carrier system significantly improved the delivery and adsorption of black tea extracts onto hair surfaces in vitro, suggesting its potential as a hair dye and protective agent.

This study found that components derived from Sansevieria trifasciata demonstrated notable antibacterial activity against Escherichia coli and Streptococcus aureus, highlighting potential for developing new antibacterial agents.

This study found that volatile organic compounds from Bacillus subtilis strain WM13-24 enhanced root development in Arabidopsis and its host plant through auxin signaling.

This review suggests that the compound DRDE-07, originally a sulphur-mustard countermeasure candidate, could potentially be repurposed for skin protection due to its compatibility with pathways involved in oxidative stress and inflammation, though further experimental study is needed to confirm its therapeutic applicability in dermatology.

This study reports that compound heterozygous loss-of-function mutations in the HEPHL1 gene in a child were associated with abnormal hair and cognitive issues, linking altered ferroxidase activity to hair disorders.

Using a transgenic pig model, this study demonstrated that LGR5 is a marker of hair follicle stem cells across different species, with important similarities and differences in gene expression and developmental processes.

In this study, researchers observed that alopecia prevalence varies in gray bats throughout the summer, with higher rates in lactating females, who also exhibit more severe lesions, but found no link between subcutaneous mites and fur loss.

This study found that Avicennia marina extract and its active compound avicequinone C inhibit enzymes and receptors related to androgenic alopecia, potentially supporting hair growth in cultured dermal papilla cells.

This article reviews innovations in hair cosmetics, focusing on esthetic procedures and products in the Indian market, and reports no new experimental findings.

This review summarizes recent findings on how the dysregulated PI3K/Akt/mTOR pathway contributes to immune-mediated inflammatory skin disorders and discusses the potential of natural products, synthetic compounds, and biologic agents in their treatment. However, it emphasizes the need for further research to develop effective therapies.

Results are not reported for this study exploring how herbal hair dye, made from natural plant-based ingredients, might promote glossier, longer, and thicker hair while covering gray.

This study found that Nubian ibex have developed genetic adaptations in response to their desert environment, including enhanced skin barrier, DNA repair, viral response, and metabolism of toxic compounds.

In this study, male rats exposed in utero to low-dose chemical mixtures had permanent reproductive tract alterations, suggesting additive effects even at doses below individual adverse levels.

In this mouse study, UVA and UVB exposure led to hair follicle miniaturization, graying, and prolonged hair cycle duration, associated with changes in stem cells and increased Wnt signaling activity.

This study found that a 5% gel with hydroalcoholic extract from black pop bean integument may have a photoprotective effect in mice exposed to UV-C radiation.

This study found that cardamonin may inhibit OSCC cell migration, proliferation, and invasion by affecting the PI3K/AKT pathway, suggesting its potential as a treatment.

This study in mutant mice found that Bmpr2 and Acvr2a are individually redundant, but together essential for normal hair follicle development, with their reduction causing rapid hair cycling and graying.

This review highlights the potential of marine macroalgae as a largely untapped resource for developing new active ingredients in the cosmetic industry, emphasizing their role in supporting circular economy models by utilizing waste from other industrial sectors.

This review reports on the traditional and ethnopharmacological uses of Ziziphus jujuba Mills, noting its increasing global popularity for treating various ailments, but highlights that its acceptance into the European Pharmacopoeia remains unresolved due to scientific and regulatory challenges.